--- title: Buy Vesicare Solifenacin 5mg/10mg Pills description: Vesicare (Solifenacin) helps manage overactive bladder symptoms effectively. Order these trusted urinary control pills from our verified online pharmacy. type: product language: en url: https://liabilis.com/order-vesicare-online-en.html availability: in_stock shipping: - type: Standard Airmail price: 10.00 currency: USD area: Worldwide time: 14-21 days - type: Tracked Express price: 30.00 currency: USD area: Worldwide tracking: true time: 5-9 days price_min: 91.19 price_max: 523.44 currency: USD offers: - name: 5mg x 30 pills price: 91.19 - name: 5mg x 60 pills price: 148.19 - name: 5mg x 90 pills price: 220.99 - name: 5mg x 120 pills price: 261.24 - name: 5mg x 180 pills price: 374.29 - name: 10mg x 30 pills price: 116.99 - name: 10mg x 60 pills price: 200.44 - name: 10mg x 90 pills price: 296.39 - name: 10mg x 120 pills price: 402.99 - name: 10mg x 180 pills price: 523.44 --- # Buy Vesicare Solifenacin 5mg/10mg Pills Vesicare, containing solifenacin succinate, is an antimuscarinic medication originally developed by Astellas Pharma for overactive bladder treatment. It helps reduce urinary frequency, urgency, and incontinence by relaxing bladder muscles, providing relief for adults struggling with bladder control issues. This medication offers significant improvement in quality of life for those with OAB symptoms. We provide Vesicare in 5mg and 10mg pill strengths through our reliable pharmacy service. ## Pricing and Options | Dosage | Pack Size | Price (USD) | Price Per Pill | Status | | :--- | :--- | :--- | :--- | :--- | | **5mg** | 30 pills | **$91.19** | $3.04 | In Stock | | **5mg** | 60 pills | **$148.19** | $2.47 | In Stock | | **5mg** | 90 pills | **$220.99** | $2.46 | In Stock | | **5mg** | 120 pills | **$261.24** | $2.18 | In Stock | | **5mg** | 180 pills | **$374.29** | $2.08 | In Stock | | **10mg** | 30 pills | **$116.99** | $3.90 | In Stock | | **10mg** | 60 pills | **$200.44** | $3.34 | In Stock | | **10mg** | 90 pills | **$296.39** | $3.30 | In Stock | | **10mg** | 120 pills | **$402.99** | $3.36 | In Stock | | **10mg** | 180 pills | **$523.44** | $2.91 | In Stock | [Buy Now](https://liabilis.com/order-vesicare-online-en.html) ## Introduction Vesicare is a medication used to treat symptoms of an overactive bladder, such as sudden urges to urinate, frequent daytime urination, and nighttime urination. The active ingredient is solifenacin, and it is supplied as an oral tablet in two strengths: 5 mg and 10 mg. Vesicare belongs to the class of antimuscarinic agents, which work by reducing involuntary bladder muscle contractions. It is prescribed for adults who experience urgency, urge incontinence, or both, and may also be used to manage urinary frequency and nocturia when these symptoms are not adequately controlled by non-pharmacologic measures. ## Quick Reference Facts **Active Ingredient** : Solifenacin **Form** : Pill 5 mg | 10 mg **Primary Uses** : • Urge urinary incontinence : • Overactive bladder with urgency : • Frequency and nocturia associated with overactive bladder ## What is Vesicare? Vesicare is the generic version of medications that contain the active compound solifenacin. Solifenacin is the pharmacologic agent responsible for the therapeutic effects of Vesicare. The drug is marketed under the well-known brand name Vesicare and may also appear as generic solifenacin tablets distributed by multiple manufacturers. As a generic product, Vesicare offers the same clinical efficacy and safety profile as the brand version while typically providing a lower cost to patients. It is manufactured by licensed pharmaceutical firms that adhere to international Good Manufacturing Practices (GMP). ## How Vesicare Works Solifenacin exerts its effect by selectively blocking muscarinic M₃ receptors in the detrusor muscle of the bladder. These receptors mediate acetylcholine-induced contraction of the bladder wall. By antagonizing M₃ receptors, Vesicare reduces involuntary bladder contractions without markedly affecting normal bladder emptying. The drug shows a higher affinity for M₃ than for other muscarinic subtypes, which helps limit systemic anticholinergic side effects. After oral administration, solifenacin is absorbed rapidly, reaching peak plasma concentrations within 3-4 hours. It is metabolized primarily by the hepatic enzyme CYP3A4 and eliminated through both renal and fecal pathways, with a terminal half-life of approximately 45-68 hours, allowing once-daily dosing. ## Conditions Treated with Vesicare - **Urgency urinary incontinence** - Vesicare diminishes sudden, uncontrollable urges to void, decreasing episodes of leakage. - **Overactive bladder (OAB)** - By relaxing the detrusor muscle, the medication lowers the frequency of involuntary contractions that cause urgency and frequency. - **Urinary frequency** - Patients report fewer daytime voids because the bladder contracts less often. - **Nocturia associated with OAB** - Reduced nighttime bladder activity leads to fewer awakenings to urinate. Each of these indications is supported by regulatory approval in major jurisdictions, based on randomized controlled trials that demonstrated statistically and clinically significant improvements in symptom scores compared with placebo. ## Is Vesicare the Right Medication for You? Vesicare is appropriate for adults with documented overactive bladder symptoms who have not achieved sufficient relief from behavioral therapies (e.g., bladder training, fluid management). It is especially useful when urgency or urge incontinence significantly impacts quality of life. The medication is contraindicated in individuals with urinary retention, severe gastric retention, uncontrolled narrow-angle glaucoma, or known hypersensitivity to solifenacin. Caution is advised in patients with moderate to severe hepatic impairment, renal insufficiency, or a history of cardiac arrhythmias, as dose adjustments may be necessary. Elderly patients may be more susceptible to anticholinergic side effects such as dry mouth and constipation, so clinicians often start with the 5 mg dose and titrate based on tolerance and efficacy. ## Buying Vesicare from [our online pharmacy](https://liabilis.com/order-vesicare-online-en.html) ### Why Choose Our Service? Accessing Vesicare can be challenging when insurance coverage is limited or local pharmacies experience stock shortages. [our online pharmacy](https://liabilis.com/order-vesicare-online-en.html) provides a convenient, cost-effective route to obtain the medication, helping you maintain your treatment plan without interruption. ### Quality & Safety Assurance We partner with licensed international pharmacies to ensure quality and authenticity. Every shipment is sourced from manufacturers that comply with recognized regulatory standards, guaranteeing that you receive a product that meets the same specifications as the brand-name version. ### Pricing & Access Because Vesicare is a generic formulation, it is offered at a price close to the manufacturer’s cost, representing a substantial saving compared with branded alternatives. Our platform makes the medication readily available to patients in regions where it might otherwise be difficult to obtain. ### Discreet Delivery Your privacy is a priority. Orders are packaged in plain, unmarked envelopes and dispatched via secure carriers, typically arriving within 7 days with express service or about three weeks with standard airmail. Choosing our pharmacy service means you receive a reliable supply of Vesicare while benefiting from transparent pricing, verified quality, and confidential shipping. ## Use: Dosing, Missed Dose, Overdose - **Standard dosing**: The usual starting dose is 5 mg taken once daily with or without food. Depending on therapeutic response and tolerability, the dose may be increased to 10 mg once daily. - **Missed dose**: If you forget a dose, take it as soon as you remember unless it is within 12 hours of the next scheduled dose. In that case, skip the missed dose and resume the regular schedule-do not double-dose. - **Overdose**: Symptoms may include severe dry mouth, extreme constipation, blurred vision, or urinary retention. Seek immediate medical attention or contact a poison control center. - **Administration tips**: Vesicare can be taken with meals, but avoid consuming large amounts of alcohol as it may intensify anticholinergic effects. Do not operate heavy machinery or drive if you experience dizziness or visual disturbances. ## Safety Information ### ⚠️ Who Should Not Take Vesicare - Individuals with urinary retention or significant bladder outlet obstruction. - Patients with uncontrolled narrow-angle glaucoma. - Those with severe hepatic impairment (Child-Pugh class C). - Anyone who has experienced a severe hypersensitivity reaction to solifenacin or any tablet excipients. ### Common Side Effects - **Dry mouth** - Occurs in up to 30 % of patients; manage with frequent sips of water and sugar-free lozenges. - **Constipation** - Use dietary fiber, increased fluid intake, and mild laxatives if needed. - **Blurred vision** - Usually mild and transient; report persistent visual changes to your clinician. ### Serious Side Effects (Seek Immediate Medical Help) - **Acute urinary retention** - Inability to pass urine may require catheterization. - **Severe allergic reaction** - Symptoms include rash, itching, swelling, severe dizziness, or trouble breathing. - **Cardiac arrhythmias** - Rare reports of QT prolongation; seek urgent care if you experience palpitations or fainting. ### Drug & Food Interactions - **CYP3A4 inhibitors** (e.g., ketoconazole, erythromycin) - May raise solifenacin levels, increasing side-effect risk. - **CYP3A4 inducers** (e.g., rifampin, phenytoin) - May lower effectiveness by decreasing drug concentration. - **Other anticholinergics** - Concomitant use can amplify dry mouth, constipation, and blurred vision. - **Alcohol** - Can intensify anticholinergic adverse effects; moderation is advised. ## Off-Label and Investigational Uses of Vesicare Clinical studies have explored solifenacin for neurogenic detrusor overactivity in patients with spinal cord injury or multiple sclerosis, showing modest reductions in urgency episodes. Some urologists also prescribe it off-label for patients with refractory interstitial cystitis when conventional therapies have failed. These uses are not approved by regulatory agencies, and any off-label treatment should only be undertaken under the direct supervision of a qualified healthcare professional. ## Storage & Handling - Store tablets at controlled room temperature (20-25 °C/68-77 °F). - Protect from excess heat, moisture, and direct sunlight. - Keep the container tightly closed and out of reach of children. - Do not use tablets beyond the printed expiration date. - Dispose of unused medication in accordance with local pharmacy or hazardous waste guidelines. ## Frequently Asked Questions **Practical Use & Lifestyle** - **Can I travel internationally with Vesicare?** Yes, but carry the medication in its original container with a copy of the prescription, and be aware of the destination country’s import regulations for prescription drugs. - **Does Vesicare interact with caffeine?** Caffeine has mild stimulatory effects on the bladder but is not a known pharmacokinetic interaction. Excessive caffeine may worsen urgency, so moderate intake is advisable. - **Is it safe to take Vesicare while exercising?** Regular physical activity is encouraged. If you experience dizziness or blurred vision, pause intense workouts until symptoms resolve. **Product Information** - **What do Vesicare tablets look like?** Vesicare tablets are round, white to off-white, and imprinted with “5” or “10” to indicate strength. Appearance may vary slightly between manufacturers. - **Can the tablets be split?** The 5 mg tablets are scored and may be divided if a lower dose is required, but the 10 mg tablets are not scored and should be taken whole. **Regulatory & Safety Nuances** - **Will Vesicare show up on a drug test for athletes?** Solifenacin is not a prohibited substance on major anti-doping agencies’ lists, but athletes should verify with their governing body. - **Is Vesicare safe during pregnancy?** It is classified as Pregnancy Category C; animal studies have shown risk, and there are no adequate human studies. Use only if the potential benefit justifies the potential risk and after consulting a healthcare provider. - **Can older adults take Vesicare without dose adjustment?** Elderly patients often start at 5 mg due to increased susceptibility to anticholinergic effects; dose may be increased cautiously if tolerated. **Scientific & Clinical Curiosity** - **How was solifenacin discovered?** Solifenacin was synthesized in the 199s as part of a series of selective muscarinic antagonists aimed at improving bladder control with fewer systemic side effects. - **What key trials supported its approval?** Two pivotal Phase III trials (SCI-111 and SOL-102) demonstrated statistically significant reductions in urgency episodes compared with placebo, leading to regulatory approval in the early 200s. - **Does Vesicare affect heart rhythm?** Rare cases of QT interval prolongation have been reported, especially when combined with other QT-prolonging agents. Baseline ECG monitoring is recommended for patients with known cardiac risk factors. ## Glossary **Antimuscarinic** : A class of drugs that block muscarinic acetylcholine receptors, reducing involuntary smooth-muscle contractions. **Detrusor muscle** : The smooth muscle layer of the bladder wall responsible for contracting to expel urine. **CYP3A4** : An enzyme in the liver that metabolizes many medications; inhibitors can raise drug levels, while inducers can lower them. **QT prolongation** : An extension of the heart’s electrical repolarization period, which can increase the risk of arrhythmias. **Overactive bladder (OAB)** : A syndrome characterized by urgency, with or without urge incontinence, usually accompanied by increased daytime frequency and nocturia. ## Disclaimer The information provided about **Vesicare** is for general knowledge only. It does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. **[our online pharmacy](https://liabilis.com/order-vesicare-online-en.html)** offers access to **Vesicare** for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.