--- title: Buy Theophylline 400mg Pills Online description: Theophylline is a bronchodilator medication for asthma and COPD symptoms. Order 400mg pills from our trusted online pharmacy for respiratory support. type: product language: en url: https://liabilis.com/order-theophylline-online-en.html availability: in_stock shipping: - type: Standard Airmail price: 10.00 currency: USD area: Worldwide time: 14-21 days - type: Tracked Express price: 30.00 currency: USD area: Worldwide tracking: true time: 5-9 days price_min: 26.59 price_max: 255.99 currency: USD offers: - name: 400mg x 30 pills price: 26.59 - name: 400mg x 60 pills price: 43.69 - name: 400mg x 90 pills price: 49.99 - name: 400mg x 120 pills price: 52.24 - name: 400mg x 180 pills price: 138.99 - name: 400mg x 360 pills price: 255.99 --- # Buy Theophylline 400mg Pills Online Theophylline is a bronchodilator medication that helps treat respiratory conditions including asthma, chronic bronchitis, and emphysema. It works by relaxing the muscles in the lungs and chest, making breathing easier and improving airflow. This medication is designed for adults managing chronic respiratory disorders. Our online pharmacy offers reliable access to generic Theophylline in 400mg pill form for effective breathing support. ## Pricing and Options | Dosage | Pack Size | Price (USD) | Price Per Pill | Status | | :--- | :--- | :--- | :--- | :--- | | **400mg** | 30 pills | **$26.59** | $0.88 | In Stock | | **400mg** | 60 pills | **$43.69** | $0.73 | In Stock | | **400mg** | 90 pills | **$49.99** | $0.56 | In Stock | | **400mg** | 120 pills | **$52.24** | $0.44 | In Stock | | **400mg** | 180 pills | **$138.99** | $0.77 | In Stock | | **400mg** | 360 pills | **$255.99** | $0.71 | In Stock | [Buy Now](https://liabilis.com/order-theophylline-online-en.html) ## Introduction Theophylline is a methyl-xanthine medication used primarily to relax the smooth muscle of the airways and improve breathing. It contains the active compound theophylline and is supplied as a 400 mg oral pill. Classified as a bronchodilator, the drug is indicated for chronic obstructive pulmonary disease (COPD) and asthma when other treatments are insufficient. Secondary uses include management of nocturnal asthma symptoms and, in some clinical settings, treatment of premature infant apnea. ## Quick Reference Facts **Active Ingredient** : Theophylline **Form** : pill 400 mg **Primary Uses** : • Long-term control of asthma • Maintenance therapy for COPD ## What is Theophylline? Theophylline is the generic version of medications containing the active compound theophylline. It belongs to the methyl-xanthine class of bronchodilators, which also includes caffeine and theobromine. Historically, the drug was introduced in the 195s and has been used worldwide for respiratory disorders. Commercially, theophylline is marketed under brand names such as Theo-Dur, Elixophyllin, and Phyllocontin. As a generic product, it is bioequivalent to these branded formulations and offers a cost-saving alternative for patients who require long-term therapy. ## How Theophylline Works Theophylline exerts its therapeutic effect mainly by inhibiting phosphodiesterase (PDE) enzymes, leading to increased intracellular cyclic adenosine monophosphate (cAMP). Elevated cAMP relaxes bronchial smooth muscle, resulting in bronchodilation. The drug also antagonizes adenosine receptors, which contributes to reduced airway inflammation and improved diaphragmatic contractility. Onset of action after oral administration occurs within 30-60 minutes, with a duration of effect lasting 8-12 hours, depending on individual metabolism. Theophylline is metabolized primarily by hepatic cytochrome P450 isoenzymes (CYP1A2, CYP2E1) and eliminated via renal excretion; serum concentrations are therefore influenced by factors such as smoking, liver function, and concomitant medications. ## Conditions Treated with Theophylline - **Asthma (maintenance therapy)** Theophylline reduces bronchial hyper-responsiveness and helps control chronic symptoms when inhaled corticosteroids and long-acting β₂-agonists are inadequate. - **Chronic Obstructive Pulmonary Disease (COPD)** By relaxing airway smooth muscle, theophylline improves airflow limitation and exercise tolerance in stable COPD patients. - **Nocturnal asthma** The drug’s long half-life can mitigate night-time bronchoconstriction, decreasing awakenings due to asthma symptoms. ## Is Theophylline the Right Medication for You? Theophylline is appropriate for adults with persistent asthma or COPD who have not achieved optimal control with inhaled therapies alone. It is especially useful when oral medication is preferred for ease of adherence. The drug is less suitable for patients with a history of cardiac arrhythmias, uncontrolled seizures, severe hepatic impairment, or those who are pregnant without careful monitoring. Because therapeutic levels vary widely between individuals, regular serum concentration checks are recommended to maintain efficacy while avoiding toxicity. ## Buying Theophylline from [our online pharmacy](https://liabilis.com/order-theophylline-online-en.html) ### Why Choose Our Service? Access to affordable, high-quality medications can be challenging, especially for chronic therapies like theophylline. [our online pharmacy](https://liabilis.com/order-theophylline-online-en.html) streamlines acquisition, offering a reliable source for the 400 mg oral tablets at a price close to manufacturer cost. ### Quality & Safety Assurance We partner with licensed international pharmacies to ensure quality and authenticity. Every batch of theophylline we dispense meets the regulatory standards of the country of manufacture and is verified by independent pharmacists. ### Pricing & Access Because theophylline is available as a generic, our platform provides significant cost savings compared with brand-name equivalents such as Theo-Dur or Elixophyllin. This makes long-term therapy more financially sustainable for patients who require daily dosing. ### Discreet Delivery Orders are packaged in unmarked, tamper-evident envelopes and shipped via express courier within 7 days or standard airmail in approximately 3 weeks. Your privacy is protected throughout the process. ## Use: Dosing, Missed Dose, Overdose - **Standard dosing** Adults typically start with 200 mg twice daily (total 400 mg/day). Depending on serum levels, the dose may be increased to a maximum of 600 mg/day, often administered as 300 mg every 12 hours. Our 400 mg tablets are usually taken once daily after a physician-determined titration. - **Missed dose** If a dose is forgotten and it has been less than 8 hours since the scheduled time, take it promptly. If more than 8 hours have passed, skip the missed dose and resume the regular schedule; do not double-dose. - **Overdose** Suspected overdose (e.g., ingestion of >1 g) requires immediate medical attention. Symptoms may include severe nausea, vomiting, seizures, or cardiac arrhythmias. Call emergency services and provide details of the amount taken. - **Practical precautions** • Take theophylline with food to lessen gastrointestinal upset. • Avoid excessive caffeine, as it may increase side-effects. • Do not operate heavy machinery until you know how the medication affects you, especially during dose adjustments. ## Safety Information ### ⚠️ Who Should Not Take Theophylline - Known hypersensitivity to theophylline or other methyl-xanthines - Uncontrolled cardiac arrhythmias (e.g., atrial fibrillation, ventricular tachycardia) - Active seizure disorders not stabilized with medication - Severe hepatic impairment (Child-Pugh C) - Pregnant women unless benefits outweigh risks and serum levels are closely monitored ### Common Side Effects - Nausea, vomiting, or abdominal discomfort (mild, often transient) - Headache and insomnia (dose-related; may improve with dose reduction) - Tremor or mild palpitations (typically resolve with therapeutic monitoring) ### Serious Side Effects (Seek Immediate Medical Help) - New or worsening cardiac arrhythmias (e.g., rapid irregular heartbeat) - Seizures or convulsions, especially at serum concentrations >30 µg/mL - Severe allergic reactions (rash, swelling, difficulty breathing) ### Drug & Food Interactions - **Cimetidine, ciprofloxacin, erythromycin, and fluoroquinolones** - inhibit metabolism, raising theophylline levels; dose adjustment may be required. - **Rifampin, carbamazepine, smoking** - induce metabolism, lowering concentrations; higher doses may be needed. - **Alcohol** - can increase central nervous system depression and potentiates toxicity. - **Caffeine-rich foods/drinks** - additive stimulant effect, may heighten nervous system side-effects. ## Off-Label and Investigational Uses of Theophylline - **Apnea of prematurity** - clinical studies have shown that low-dose theophylline can stimulate respiration in preterm infants, reducing apnea episodes. Use is considered off-label and requires neonatal intensive-care supervision. - **Obstructive sleep apnea (adult)** - small trials suggest modest improvement in upper-airway muscle tone; however, safety and efficacy have not been established for routine use. - **Bronchopulmonary dysplasia** - investigational protocols explore theophylline’s anti-inflammatory properties in chronic lung disease of infancy. All off-label applications should be undertaken only under direct care of a qualified healthcare professional. ## Storage & Handling - Store tablets at 20-25 °C (68-77 °F) in a dry place, protected from moisture and direct sunlight. - Keep the container tightly closed and out of reach of children. - Do not use tablets beyond the expiration date printed on the packaging. - Dispose of unused medication according to local hazardous-waste regulations or return to a pharmacist for proper disposal. ## Frequently Asked Questions **Practical Use & Lifestyle** - **Can I travel internationally with theophylline tablets?** Yes, but keep them in the original labeled container, carry a copy of the prescription, and be aware of import restrictions in the destination country. - **Will caffeine consumption affect my theophylline dose?** Caffeine adds to the overall methyl-xanthine load and may increase side-effects such as jitteriness or insomnia. Moderate intake is advisable, and any significant changes should be discussed with your clinician. - **Is it safe to take theophylline while exercising?** Theophylline can increase heart rate; if you notice palpitations or dizziness during activity, reduce intensity and consult your healthcare provider. **Product & Formulation Details** - **What do Theophylline 400 mg tablets look like?** They are typically round, white to off-white, and may be film-coated. In different regions, tablet imprint markings can vary; check the label for the manufacturer’s identifier. - **Can the tablets be split or crushed?** Theophylline tablets are not formulated for extended-release; they may be split if a lower dose is needed, but crushing can alter absorption and is not recommended without pharmacist advice. **Regulatory & Safety Nuances** - **Will theophylline appear on a standard drug test?** Theophylline is not generally screened for in routine occupational drug testing, which typically targets substances of abuse such as opioids, cannabinoids, and stimulants. - **Is theophylline contraindicated for elderly patients?** Age-related decline in hepatic metabolism can raise serum levels, making careful dose titration and monitoring essential for older adults. - **How does smoking affect my theophylline therapy?** Smoking induces CYP1A2, accelerating theophylline clearance and potentially reducing efficacy. Smokers often require higher maintenance doses, and dose adjustments should be made under medical supervision. **Scientific & Clinical Curiosity** - **When was theophylline first approved for asthma?** Theophylline received its first regulatory approval for asthma management in the early 195s, shortly after its discovery as a bronchodilator. - **How does theophylline compare with newer inhaled medications?** While inhaled corticosteroids and long-acting β₂-agonists provide targeted airway relief with fewer systemic effects, theophylline offers an oral alternative that can be useful when inhaler technique is suboptimal or when cost constraints limit access to newer agents. ## Glossary **Therapeutic Window** : The range of drug blood concentrations that provides clinical benefit without causing unacceptable toxicity. **Bioavailability** : The proportion of an administered dose that reaches systemic circulation in an active form. **Serum Concentration** : The measured amount of drug present in the blood, usually expressed in micrograms per milliliter (µg/mL). **Cytochrome P450** : A family of liver enzymes responsible for metabolizing many medications, including theophylline. **Half-Life** : The time required for the plasma concentration of a drug to reduce by 50 %. ## Disclaimer The information presented about **Theophylline** serves solely as general educational material and is not a substitute for professional medical advice. Treatment choices, including any off-label applications, must be determined under the guidance of a qualified healthcare practitioner. Readers are presumed to be competent adults capable of making informed health decisions. Our pharmacy service supplies Theophylline for individuals who may encounter limited access through conventional pharmacies, insurance formularies, or who are seeking cost-effective generic options. Always discuss any medication changes with your physician before initiating, adjusting, or discontinuing therapy.