--- title: Buy Nintedanib 100mg Capsules Online description: Nintedanib 100mg Capsules is a trusted treatment for idiopathic pulmonary fibrosis. Order from our secure pharmacy for reliable respiratory care. type: product language: en url: https://liabilis.com/order-nintedanib-online-en.html availability: in_stock shipping: - type: Standard Airmail price: 10.00 currency: USD area: Worldwide time: 14-21 days - type: Tracked Express price: 30.00 currency: USD area: Worldwide tracking: true time: 5-9 days price_min: 183.34 price_max: 745.74 currency: USD offers: - name: 100mg x 30 caps price: 183.34 - name: 100mg x 60 caps price: 313.49 - name: 100mg x 90 caps price: 454.99 - name: 100mg x 120 caps price: 523.44 - name: 100mg x 180 caps price: 745.74 --- # Buy Nintedanib 100mg Capsules Online Nintedanib is a tyrosine kinase inhibitor originally developed by Boehringer Ingelheim that is used to treat idiopathic pulmonary fibrosis (IPF) by slowing lung scarring and disease progression. It is also used for certain types of interstitial lung diseases. This specialized medication is designed for adults managing progressive lung conditions. Our pharmacy provides reliable access to Nintedanib in 100mg capsules with secure shipping. ## Pricing and Options | Dosage | Pack Size | Price (USD) | Price Per Pill | Status | | :--- | :--- | :--- | :--- | :--- | | **100mg** | 30 caps | **$183.34** | $6.11 | In Stock | | **100mg** | 60 caps | **$313.49** | $5.22 | In Stock | | **100mg** | 90 caps | **$454.99** | $5.06 | In Stock | | **100mg** | 120 caps | **$523.44** | $4.36 | In Stock | | **100mg** | 180 caps | **$745.74** | $4.14 | In Stock | [Buy Now](https://liabilis.com/order-nintedanib-online-en.html) ## Introduction Nintedanib is a small-molecule tyrosine-kinase inhibitor indicated for the treatment of progressive fibrotic lung diseases in adults. The medication contains the active ingredient nintedanib and is supplied as 100 mg capsules (cap). It belongs to the class of antifibrotic agents that target pathways involved in tissue scarring. In addition to idiopathic pulmonary fibrosis (IPF), it is approved for chronic fibrosing interstitial lung diseases associated with systemic sclerosis and other progressive fibrosing conditions. ## Quick Reference Facts ``` **Active Ingredient** : Nintedanib **Form: cap 100 mg **Primary Uses** : • Idiopathic pulmonary fibrosis (IPF) • Systemic sclerosis-associated interstitial lung disease (SSc-ILD) • Other progressive fibrosing interstitial lung diseases (PF-ILD) ``` ## What is Nintedanib? Nintedanib is the generic version of medications containing the active compound nintedanib. It is marketed under brand names such as **Ofev** and **Vargatef**, which were developed by Boehringer Ingelheim. The generic formulation provides the same pharmacological activity as the branded products and is approved by major regulatory agencies, including the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA). Because it is a generic, it offers a cost-effective alternative while meeting the same rigorous quality standards required for pharmaceutical products. ## How Nintedanib Works Nintedanib inhibits multiple receptor tyrosine kinases, including those for platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), and vascular endothelial growth factor (VEGF). By blocking these pathways, the drug reduces the proliferation, migration, and transformation of fibroblasts into myofibroblasts-cells that drive excessive extracellular matrix deposition in the lungs. The net effect is a slowdown in the rate of fibrotic remodeling, preserving lung function and reducing the decline in forced vital capacity (FVC) over time. Nintedanib is metabolized primarily by esterases and excreted unchanged in the feces; the half-life is approximately 9-13 hours, supporting twice-daily dosing. ## Conditions Treated with Nintedanib - **Idiopathic Pulmonary Fibrosis (IPF)** - Nintedanib is approved to slow disease progression in adult patients with IPF, a chronic, irreversible scarring of the lung parenchyma. Clinical trials (e.g., INPULSIS-1 and INPULSIS-2) demonstrated a reduction in annual FVC decline compared with placebo. - **Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)** - In patients with systemic sclerosis, lung involvement is a leading cause of mortality. Nintedanib improves lung function by reducing the rate of FVC loss, as shown in the SENSCIS trial. - **Other Progressive Fibrosing Interstitial Lung Diseases (PF-ILD)** - For a broader group of fibrotic lung diseases that share a progressive phenotype, nintedanib is approved to attenuate functional decline, based on data from the INBUILD study. ## Is Nintedanib the Right Medication for You? Nintedanib is appropriate for adult patients with a confirmed diagnosis of IPF, SSc-ILD, or other PF-ILDs who have demonstrable disease progression despite optimal supportive care. It is most beneficial when initiated early in the disease course, as the antifibrotic effect is proportional to ongoing fibroblast activity. Contraindications include severe hepatic impairment, uncontrolled bleeding disorders, and known hypersensitivity to nintedanib or any excipients. Caution is advised in patients with moderate hepatic dysfunction, those taking anticoagulants, and individuals at high risk for gastrointestinal complications. Regular monitoring of liver enzymes, hemoglobin, and body weight is recommended to ensure safe continuation of therapy. ## Buying Nintedanib from [our online pharmacy](https://liabilis.com/order-nintedanib-online-en.html) ### Why Choose Our Service? Accessing nintedanib can be challenging due to high price points or limited stock in some regions. [our online pharmacy](https://liabilis.com/order-nintedanib-online-en.html) provides a reliable avenue for obtaining the generic formulation at a price close to the manufacturer’s cost, helping patients maintain their prescribed treatment without financial strain. ### Quality & Safety Assurance We partner with licensed international pharmacies to ensure quality and authenticity. Every shipment undergoes verification against regulatory standards, guaranteeing that the capsules you receive meet the same specifications as brand-name equivalents. ### Pricing & Access Because this is the generic version, the cost is substantially lower than branded alternatives such as Ofev. Our platform also offers discreet, streamlined ordering that bypasses typical supply-chain bottlenecks, making the medication more readily available for patients worldwide. ### Discreet Delivery Orders are packaged in unmarked, tamper-evident envelopes and dispatched via express courier (typically within 7 days) or standard airmail (approximately three weeks). Privacy is maintained throughout the process, and tracking information is provided for every shipment. ## Use: Dosing, Missed Dose, Overdose - **Standard Dosing** - Adults receive **two 100 mg capsules once daily** (total 200 mg) with food to minimize gastrointestinal upset. The dose may be reduced to 100 mg once daily if tolerability issues arise. - **Missed Dose** - If a dose is missed and the next scheduled dose is more than 12 hours away, take the missed dose as soon as you remember. If the interval is shorter, skip the missed dose and resume the regular schedule. Do not double-dose. - **Overdose** - In the event of a suspected overdose, seek immediate medical attention. Overdose symptoms may include severe nausea, vomiting, diarrhea, and elevated liver enzymes. Supportive care is the mainstay of treatment. - **Practical Precautions** - Take nintedanib with meals to reduce the risk of diarrhea. - Avoid concomitant use of strong CYP3A4 inhibitors (e.g., itraconazole) as they may increase exposure. - Refrain from operating heavy machinery if you experience dizziness or fatigue until you know how the medication affects you. ## Safety Information ### ⚠️ Who Should Not Take Nintedanib - Patients with severe hepatic impairment (Child-Pugh C). - Individuals with active, clinically significant bleeding (e.g., recent gastrointestinal hemorrhage). - Known hypersensitivity to nintedanib or any capsule excipients. ### Common Side Effects - **Diarrhea** (most frequent; occurs in up to 60 % of patients). Usually mild to moderate; dose reduction often helps. - **Nausea and vomiting** - can be mitigated by taking the medication with food. - **Elevated liver enzymes** - monitor ALT/AST regularly; discontinue if levels exceed three times the upper limit of normal. ### Serious Side Effects (Seek Immediate Medical Help) - **Severe gastrointestinal bleeding** - black stools, vomiting blood, or sudden abdominal pain. - **Significant liver injury** - jaundice, dark urine, persistent fatigue. - **Serious hypersensitivity reactions** - rash, itching, swelling of face or throat, difficulty breathing. ### Drug & Food Interactions - **Anticoagulants (e.g., warfarin, direct oral anticoagulants)** - Nintedanib may increase bleeding risk; close monitoring of coagulation parameters is advised. - **Strong CYP3A4 inhibitors (ketoconazole, clarithromycin)** - May raise nintedanib plasma concentrations; dose adjustment or avoidance is recommended. - **Strong CYP3A4 inducers (rifampicin, carbamazepine)** - Can lower drug exposure, potentially reducing efficacy; avoid concurrent use if possible. - **Antacids containing aluminum or magnesium** - May reduce absorption; separate administration by at least 2 hours. ## Off-Label and Investigational Uses of Nintedanib - **Non-Small Cell Lung Cancer (NSCLC)** - Early-phase studies have examined nintedanib in combination with chemotherapy for advanced NSCLC. While some trials suggested progression-free survival benefits, the combination remains investigational and is not approved for cancer treatment. - **Autoimmune-Related Fibrosis (e.g., lupus nephritis)** - Small case series have reported potential antifibrotic effects in renal fibrosis, but robust clinical data are lacking. - **Hepatic Fibrosis** - Preclinical models indicate activity against liver stellate cell activation. Human trials are ongoing, and the use remains experimental. All off-label applications should only be pursued under the direct supervision of a qualified healthcare professional, with careful assessment of risk-benefit balance. ## Storage & Handling - Store capsules at **20-25 °C (68-77 °F)** in a dry place away from direct sunlight. - Keep the container tightly closed to protect from moisture. - Do not use the medication after the printed expiry date. - For safe disposal, return unused capsules to a pharmacy or follow local hazardous waste guidelines; do not flush them. ## Frequently Asked Questions **Practical Use & Lifestyle** - **Can I travel internationally with Nintedanib?** Yes, but keep the medication in its original container with a copy of the prescription or a physician’s note. Check the destination country’s import regulations for prescription medicines before departure. - **Should I avoid alcohol while taking Nintedanib?** Moderate alcohol consumption is not contraindicated, yet excessive intake may exacerbate liver enzyme elevations. Discuss your drinking habits with a healthcare provider. - **How should I store Nintedanib during a long flight?** Keep the capsule bottle at room temperature; avoid exposure to extreme heat in cargo holds. Placing the medication in a carry-on bag helps maintain stable conditions. **Product & Formulation Details** - **What do Nintedanib capsules look like?** The generic capsules are opaque, white, and bear the imprint “NIN 100” on one side. Appearance may vary slightly among manufacturers, but the dosage strength is consistent. - **Are there any inactive ingredients I should be aware of?** Common excipients include lactose, microcrystalline cellulose, and magnesium stearate. Patients with severe lactose intolerance should consult their physician. **Regulatory & Safety Nuances** - **Will Nintedanib appear on standard drug tests for athletes?** Nintedanib is not listed on the World Anti-Doping Agency (WADA) prohibited list. However, athletes should verify any sport-specific regulations. - **Is Nintedanib safe for elderly patients?** Older adults may have reduced hepatic clearance and a higher incidence of gastrointestinal side effects. Dose adjustments and close monitoring are advised. - **Can I take Nintedanib while pregnant or breastfeeding?** Nintedanib is contraindicated during pregnancy due to potential fetal toxicity, and it is not recommended while breastfeeding. Effective contraception should be used during treatment and for at least one month after discontinuation. **Scientific & Clinical Curiosity** - **What was the pivotal trial that led to FDA** The INPULSIS-1 and INPULSIS-2 Phase III trials demonstrated that nintedanib reduced the annual rate of FVC decline by about 50 % compared with placebo in IPF patients. - **How does Nintedanib differ from pirfenidone?** Both are antifibrotic agents