--- title: Buy Itraconazole 100mg/200mg Capsules Online description: Itraconazole capsules treat fungal infections with broad-spectrum effectiveness. 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It works by inhibiting fungal cell growth and is particularly effective against difficult-to-treat fungal conditions. This treatment is designed for adults dealing with serious fungal infections that require potent antifungal therapy. Our pharmacy provides Itraconazole in 100mg and 200mg capsule formulations for comprehensive fungal treatment. ## Pricing and Options | Dosage | Pack Size | Price (USD) | Price Per Pill | Status | | :--- | :--- | :--- | :--- | :--- | | **100mg** | 20 caps | **$60.96** | $3.05 | In Stock | | **100mg** | 40 caps | **$87.11** | $2.18 | In Stock | | **100mg** | 60 caps | **$110.04** | $1.83 | In Stock | | **100mg** | 120 caps | **$182.98** | $1.53 | In Stock | | **100mg** | 180 caps | **$235.27** | $1.31 | In Stock | | **200mg** | 12 caps | **$45.82** | $3.82 | In Stock | | **200mg** | 20 caps | **$60.96** | $3.05 | In Stock | | **200mg** | 32 caps | **$90.59** | $2.83 | In Stock | | **200mg** | 60 caps | **$165.09** | $2.75 | In Stock | | **200mg** | 92 caps | **$220.46** | $2.39 | In Stock | | **200mg** | 120 caps | **$261.41** | $2.18 | In Stock | | **200mg** | 180 caps | **$352.93** | $1.96 | In Stock | [Buy Now](https://liabilis.com/order-itraconazole-online-en.html) ## Introduction Itraconazole is a systemic antifungal medication used to treat a range of serious fungal infections in adults. The active ingredient is **Itraconazole**, supplied in oral capsule form at strengths of **100 mg** and **200 mg**. It belongs to the triazole class of antifungals, which work by disrupting fungal cell-membrane synthesis. Approved indications include infections such as blastomycosis, histoplasmosis, paracoccidioidomycosis, sporotrichosis, and certain forms of candidiasis. Itraconazole is also employed when patients cannot tolerate amphotericin B or when other antifungal agents are ineffective. --- ## Quick Reference Facts ``` **Active Ingredient** : Itraconazole **Form** : cap 100 mg | 200 mg **Primary Uses** : Blastomycosis, Histoplasmosis, Paracoccidioidomycosis, Sporotrichosis, Oropharyngeal & Esophageal Candidiasis, Certain Aspergillus infections ``` --- ## What is Itraconazole? Itraconazole is the generic version of medications that contain the active compound **Itraconazole**. It is marketed under brand names such as **Sporanox** and **Onmel** in various countries. As a triazole antifungal, it is prescribed for systemic mycoses that require oral therapy. The drug is manufactured by several licensed pharmaceutical companies that meet international quality standards. Because it is a generic product, it offers the same therapeutic effect as brand-name equivalents while typically costing less for patients. --- ## How Itraconazole Works Itraconazole inhibits the fungal enzyme **lanosterol 14α-demethylase**, a member of the cytochrome P450 family. This enzyme is essential for converting lanosterol to ergosterol, a key component of the fungal cell membrane. By blocking ergosterol synthesis, the drug destabilizes the membrane, leading to increased permeability and ultimately fungal cell death. The capsule is best absorbed when taken with food, especially a meal that contains some fat, which raises gastric acidity and improves bioavailability. After absorption, Itraconazole is extensively metabolized by hepatic **CYP3A4** and has a long elimination half-life of approximately 20-30 hours, allowing once-daily dosing for many regimens. Excretion occurs mainly via the feces, with only a small fraction eliminated unchanged in the urine. --- ## Conditions Treated with Itraconazole - **Blastomycosis** - The drug penetrates lung tissue and disseminated sites, eradicating *Blastomyces dermatitidis* infections that can affect skin, bone, and the central nervous system. - **Histoplasmosis** - Effective against *Histoplasma capsulatum*, especially in chronic pulmonary disease or disseminated disease in immunocompromised patients. - **Paracoccidioidomycosis** - Used for infections caused by *Paracoccidioides* species, which are endemic in parts of Latin America. - **Sporotrichosis** - Treats cutaneous and lymphocutaneous disease caused by *Sporothrix schenckii*, offering an oral alternative to intravenous amphotericin B. - **Oropharyngeal and Esophageal Candidiasis** - Provides a convenient oral option for patients with mucosal Candida infections resistant to fluconazole or when prolonged therapy is needed. - **Aspergillus infections (selected cases)** - Employed when patients cannot tolerate amphotericin B or when drug-resistant Aspergillus species are identified. Each indication is supported by clinical trials demonstrating adequate cure rates and tolerability when the recommended dosing schedule is followed. --- ## Is Itraconazole the Right Medication for You? Itraconazole is most appropriate for adults with confirmed or highly suspected infections listed above, particularly when the pathogen is known to be susceptible in vitro. It is favored when long-term oral therapy is required, when patients have contraindications to azoles such as fluconazole, or when drug-resistance patterns limit other options. Patients with severe hepatic impairment, known hypersensitivity to triazoles, or a history of congestive heart failure should avoid Itraconazole because of the risk of hepatotoxicity and negative inotropic effects. Additionally, concurrent use of strong CYP3A4 inducers (e.g., rifampin, carbamazepine) can markedly reduce drug levels, making therapy ineffective. A thorough medication review and baseline liver-function testing are essential before initiating treatment. --- ## Buying Itraconazole from [our online pharmacy](https://liabilis.com/order-itraconazole-online-en.html) ### Why Choose Our Service? Accessing Itraconazole can be challenging due to insurance restrictions, high out-of-pocket costs, or limited local stock. [our online pharmacy](https://liabilis.com/order-itraconazole-online-en.html) provides a reliable channel to obtain the medication quickly and affordably, helping patients maintain uninterrupted therapy. ### Quality & Safety Assurance We partner with licensed international pharmacies to ensure quality and authenticity. Every batch of Itraconazole is sourced from manufacturers that comply with Good Manufacturing Practices and is verified by independent quality-control laboratories. ### Pricing & Access Because Itraconazole is available as a generic, the price is substantially lower than brand-name equivalents such as Sporanox. Our platform offers pricing that approaches the manufacturer’s wholesale cost, reducing the financial burden for patients who need long-term treatment. ### Discreet Delivery Orders are packaged in unmarked, tamper-evident envelopes and shipped via express courier, typically arriving within 7 days for most destinations. Standard airmail options are also available, with delivery in approximately three weeks. Privacy is maintained throughout the fulfillment process. --- ## Use: Dosing, Missed Dose, Overdose - **Standard Dosing** - **Blastomycosis, Histoplasmosis, Paracoccidioidomycosis:** 200 mg once daily after a loading dose of 200 mg twice daily for the first 3 days. - **Sporotrichosis:** 100 mg twice daily for 3 weeks, then 100 mg once daily for an additional 3 weeks. - **Candidiasis (oropharyngeal/esophageal):** 200 mg once daily for 14 days. - **Missed Dose** - Take the missed capsule as soon as you remember, unless it is within 6 hours of the next scheduled dose. In that case, skip the missed dose and continue with the regular schedule. Do not double-dose. - **Overdose** - If more than one extra capsule is taken, seek medical attention promptly. Symptoms may include severe nausea, vomiting, abdominal pain, or dizziness. Contact your local poison-control center or go to the nearest emergency department. - **Administration Tips** - Swallow capsules whole with a full glass of water. - Take with food to enhance absorption; a light meal containing some fat is ideal. - Avoid alcohol and operating heavy machinery until you know how the medication affects you. --- ## Safety Information ### ⚠️ Who Should Not Take Itraconazole - Known hypersensitivity to Itraconazole or any component of the capsule. - Patients with severe hepatic impairment (Child-Pugh class C). - Individuals with documented congestive heart failure (NYHA class III-IV) due to the drug’s negative inotropic effect. - Concurrent use of strong CYP3A4 inducers (e.g., rifampin, phenytoin, carbamazepine, St. John’s wort). ### Common Side Effects - **Gastrointestinal:** Nausea, vomiting, abdominal discomfort, dyspepsia. - **Neurologic:** Headache, dizziness. - **Dermatologic:** Rash, pruritus. - **Laboratory:** Mild elevations in hepatic transaminases; usually reversible after discontinuation. Most of these events are mild to moderate and resolve without intervention. ### Serious Side Effects (Seek Immediate Medical Help) - **Hepatotoxicity:** Jaundice, dark urine, severe abdominal pain, persistent nausea/vomiting. - **Cardiac Failure:** Shortness of breath, rapid weight gain, swelling of the ankles or feet, sudden onset of fatigue. - **Severe Skin Reactions:** Stevens-Johnson syndrome, toxic epidermal necrolysis, widespread rash with blistering. - **Visual Disturbances:** Blurred vision, photophobia, or sudden loss of vision. If any of these symptoms appear, discontinue Itraconazole and obtain emergency care. ### Drug & Food Interactions - **CYP3A4 Inhibitors (e.g., ketoconazole, clarithromycin, erythromycin):** May increase Itraconazole plasma concentrations → monitor for toxicity. - **CYP3A4 Inducers (e.g., rifampin, carbamazepine, St. John’s wort):** Reduce drug levels → may lead to therapeutic failure. - **Warfarin:** Itraconazole can potentiate anticoagulant effect; monitor INR closely. - **Statins (especially simvastatin, lovastatin):** Increased risk of myopathy; consider dose adjustment or alternative lipid-lowering agents. - **Oral Contraceptives:** Reduced efficacy reported; use additional non-hormonal contraception. --- ## Off-Label and Investigational Uses of Itraconazole - **Chronic Pulmonary Aspergillosis:** Small-scale studies suggest Itraconazole can suppress fungal growth in patients with cavitary lung disease when surgical options are limited. - **Prophylaxis in Hematopoietic Stem-Cell Transplantation:** Some centers employ Itraconazole to prevent invasive fungal infections, although newer agents such as posaconazole are now preferred. - **Dermatophyte Infections (e.g., tinea corporis):** Case series report successful outcomes, but evidence remains limited and not FDA-approved. - **Refractory Candidemia:** Occasionally used when fluconazole resistance is documented, though echinocandins are first-line. These applications are not officially sanctioned by regulatory agencies; they should only be considered under specialist supervision with informed consent. --- ## Storage & Handling - Store capsules at **20-25 °C (68-77 °F)** in a dry place, protected from light. - Do not refrigerate or freeze. - Keep the container tightly closed and out of reach of children. - Dispose of unused medication according to local pharmacy-take-back programs or hazardous-waste guidelines. --- ## Frequently Asked Questions **Practical Use & Lifestyle** - **Can I travel internationally with Itraconazole capsules?** Yes. Keep the medication in its original container with a copy of the prescription or a physician’s letter, as some countries require documentation for import of prescription drugs. - **Should I avoid grapefruit while taking Itraconazole?** Grapefruit juice can inhibit CYP3A4 and raise Itraconazole levels, increasing the risk of toxicity. It is advisable to limit or avoid grapefruit during therapy. - **Is it safe to take Itraconazole while drinking alcohol?** Alcohol may exacerbate liver stress. Because Itraconazole can cause hepatotoxicity, limiting alcohol consumption is prudent, especially during the first few weeks of treatment. **Product & Formulation Details** - **What do Itraconazole capsules look like?** The 100 mg capsules are typically opaque, pink-orange, and marked with “100 mg.” The 200 mg capsules are larger, opaque, and marked with “200 mg.” Appearance may vary slightly between manufacturers. - **Can I split or crush Itraconazole capsules?** No. The drug’s absorption depends on the capsule’s intact coating; splitting or crushing can lead to erratic plasma concentrations and reduced efficacy. **Regulatory & Safety Nuances** - **Will Itraconazole show up on a standard drug test?** Itraconazole is not screened for in routine employment drug panels. Specialized testing would be required to detect it, which is uncommon. - **Is Itraconazole safe for pregnant or breastfeeding women?** Animal studies have shown fetal risk, and human data are limited. It is classified as Pregnancy Category C; use only if the potential benefit justifies the potential risk. Breastfeeding is not recommended while on therapy. - **Are there any age restrictions for Itraconazole?** The medication is approved for adult use only. Safety and efficacy have not been established in patients under 18 years of age. **Scientific & Clinical Curiosity** - **When was Itraconazole first approved?** Itraconazole received FDA approval in 1992 for the treatment of systemic mycoses, expanding the therapeutic options beyond amphotericin B. - **How does Itraconazole compare to fluconazole?** Itraconazole has a broader spectrum against dimorphic fungi (e.g., *Histoplasma*, *Blastomyces*) and better activity against certain molds, whereas fluconazole is more active against *Candida* species but lacks efficacy against many systemic mycoses. --- ## Glossary **Lanosterol 14α-demethylase** : A fungal cytochrome P450 enzyme essential for converting lanosterol to ergosterol, a key component of the fungal cell membrane. **Bioavailability** : The proportion of an administered dose that reaches systemic circulation in an active form. **CYP3A4** : A major liver enzyme that metabolizes many drugs; its activity can be increased or decreased by other substances, affecting drug levels. **Negative Inotropic Effect** : A reduction in the force of heart muscle contraction, which can worsen heart failure. **Stevens-Johnson Syndrome** : A severe, life-threatening skin reaction characterized by widespread blistering and detachment of the epidermis. --- ## Disclaimer The information provided about **Itraconazole** is intended for general educational purposes and does not replace professional medical consultation. All therapeutic decisions, including those concerning off-label applications, should be made under the guidance of a qualified healthcare provider. Readers are presumed to be responsible adults capable of making informed health choices. [our online pharmacy](https://liabilis.com/order-itraconazole-online-en.html) offers access to Itraconazole for individuals who may encounter limited availability through conventional pharmacies, insurance formularies, or who seek cost-effective generic alternatives. Always discuss any medication changes, including initiation, dose adjustments, or discontinuation, with your physician or pharmacist.