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# Buy Generic Imuran (Azathioprine) 25mg/50mg Pills

Imuran, containing azathioprine, is an immunosuppressive medication that reduces the activity of the body's immune system. It is used to prevent organ transplant rejection and treat autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease. This medication is designed for adults who require immune system modulation under careful medical supervision. Our pharmacy provides access to Imuran in 25mg and 50mg pill strengths for consistent treatment management.

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| Dosage | Pack Size | Price (USD) | Price Per Pill | Status |
| :--- | :--- | :--- | :--- | :--- |
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| **25mg** | 120 pills | **$108.99** | $0.91 | In Stock |
| **50mg** | 30 pills | **$40.99** | $1.36 | In Stock |
| **50mg** | 60 pills | **$78.54** | $1.31 | In Stock |
| **50mg** | 90 pills | **$116.82** | $1.30 | In Stock |
| **50mg** | 120 pills | **$127.99** | $1.07 | In Stock |
| **50mg** | 240 pills | **$217.99** | $0.91 | In Stock |
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## Introduction

Imuran is the generic version of medications containing the active compound Azathioprine. It is supplied as a pill in strengths of 25 mg and 50 mg. Azathioprine belongs to the class of immunosuppressive antimetabolites and is primarily used to reduce abnormal immune activity in organ transplantation and several autoimmune disorders. Secondary applications include certain dermatologic and hematologic conditions where modulation of the immune system is beneficial.

## Quick Reference Facts
**Active Ingredient** 
: Azathioprine 

**Form** 
: pill 25 mg | 50 mg 

**Primary Uses** 
: Prevention of organ transplant rejection, treatment of rheumatoid arthritis, inflammatory bowel disease, systemic lupus erythematosus, and other autoimmune diseases 

## What is Imuran?

Imuran is a generic immunosuppressant medication whose active ingredient is azathioprine. It is classified as an antimetabolite that interferes with purine synthesis, thereby limiting the proliferation of rapidly dividing immune cells. The drug was originally developed in the 196s and has been incorporated into treatment protocols worldwide. Though Imuran itself is a brand name, the generic version is marketed under brand names such as Azasan and Imuran® and is available through many licensed pharmacies. Being a generic product, Imuran offers the same clinical efficacy as branded equivalents at a lower cost, meeting bioequivalence standards set by regulatory authorities.

## How Imuran Works

Azathioprine is a pro-drug that is converted in the body to 6-mercaptopurine (6-MP) and subsequently to thioguanine nucleotides. These metabolites become incorporated into cellular DNA and RNA, disrupting the synthesis of purine nucleotides. Because lymphocytes rely heavily on de novo purine synthesis for proliferation, azathioprine preferentially curtails the expansion of T and B cells, dampening the immune response. Onset of immunosuppressive effect typically occurs within 1-2 weeks, while full immunomodulation may take several weeks. The drug is metabolized primarily by the liver enzyme thiopurine methyltransferase (TPMT) and excreted renally; patients with low TPMT activity are at higher risk for bone-marrow toxicity.

## Conditions Treated with Imuran

- **Organ transplant rejection prophylaxis** 
 Azathioprine suppresses the cellular immune response that would otherwise attack transplanted tissue, reducing acute rejection rates when used with other immunosuppressants.

- **Rheumatoid arthritis** 
 By limiting autoreactive lymphocyte activity, azathioprine decreases joint inflammation and slows disease progression in patients who are intolerant of first-line disease-modifying agents.

- **Inflammatory bowel disease (Crohn’s disease and ulcerative colitis)** 
 Immunosuppression reduces mucosal inflammation, leading to fewer flare-ups and improved maintenance of remission.

- **Systemic lupus erythematosus** 
 Azathioprine helps control systemic autoimmunity, particularly in patients with renal involvement or when corticosteroid sparing is desired.

- **Autoimmune hepatitis and primary biliary cholangitis** 
 The drug attenuates hepatic immune-mediated injury, supporting liver function and delaying disease progression.

## Is Imuran the Right Medication for You?

Imuran is appropriate for adults who require long-term immunosuppression, especially when organ transplantation or severe autoimmune disease is present. Ideal candidates are those who have demonstrated tolerance to other immunosuppressants or who need steroid-sparing strategies. Patients with normal TPMT activity, adequate renal function, and no active infections are generally good candidates. Contraindications include known hypersensitivity to azathioprine, severe hepatic impairment, pregnancy (category D), and active, uncontrolled infections. Individuals with a history of malignancy should discuss risks with their healthcare provider, as immunosuppression may affect tumor surveillance.

## Buying Imuran from [our online pharmacy](https://liabilis.com/order-imuran-online-en.html)

### Why Choose Our Service?
Accessing immunosuppressive therapy can be challenging due to cost and supply constraints. Our platform delivers a reliable, affordable way to obtain Imuran without compromising safety or quality.

### Quality & Safety Assurance
We partner with licensed international pharmacies to ensure quality and authenticity.

### Pricing & Access
Because Imuran is a generic formulation, it is offered at a fraction of the price of branded equivalents, making chronic therapy more financially sustainable for patients.

### Discreet Delivery
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## Use: Dosing, Missed Dose, Overdose

**Standard Dosing (general guidance)**
- Initiation often starts at 1-2 mg/kg orally once daily, adjusted based on clinical response and TPMT activity.
- Maintenance doses usually range from 1 mg/kg to 3 mg/kg daily; some protocols split the total daily dose into two administrations.

**Missed Dose**
- If a dose is missed and the next scheduled dose is more than 12 hours away, take the missed tablet as soon as remembered.
- If the next dose is imminent, skip the missed tablet and resume the regular schedule. Do not double-dose.

**Overdose**
- In case of suspected overdose, seek emergency medical attention immediately. Symptoms may include severe nausea, vomiting, abdominal pain, and profound bone-marrow suppression.
- Contact your local poison control center and provide details of the ingested amount.

**Practical Precautions**
- Take Imuran with food or a glass of milk to reduce gastrointestinal irritation.
- Avoid excessive alcohol, which can increase liver toxicity.
- Refrain from operating heavy machinery or driving until you know how the medication affects you, especially during the initiation phase.

## Safety Information

### ⚠️ Who Should Not Take Imuran
- Individuals with known hypersensitivity to azathioprine or any of its excipients. 
- Patients with severe hepatic impairment (Child-Pugh C). 
- Pregnant women (category D) and nursing mothers, unless clearly justified. 
- Persons with active, uncontrolled infections or opportunistic pathogens. 

### Common Side Effects
- **Gastrointestinal:** Nausea, vomiting, abdominal discomfort (usually transient). 
- **Hematologic:** Mild leukopenia or thrombocytopenia; regular blood monitoring mitigates risk. 
- **Dermatologic:** Rash or mild photosensitivity.

### Serious Side Effects (Seek Immediate Medical Help)
- **Severe bone-marrow suppression:** Fever, persistent sore throat, unusual bruising or bleeding. 
- **Hepatotoxicity:** Jaundice, dark urine, severe fatigue, or right-upper-quadrant pain. 
- **Pancreatitis:** Sudden, intense abdominal pain radiating to back, accompanied by nausea.

### Drug & Food Interactions
- **Allopurinol or febuxostat:** Potentiate myelosuppression; dosage of azathioprine must be reduced. 
- **Warfarin:** May increase anticoagulant effect; monitor INR closely. 
- **Live vaccines:** Contraindicated due to impaired immune response. 
- **Certain antibiotics (e.g., sulfamethoxazole/trimethoprim):** Can enhance bone-marrow toxicity. 

## Off-Label and Investigational Uses of Imuran

- **Dermatologic conditions such as vitiligo** - small trials suggest that azathioprine may help stabilize disease progression by reducing autoimmune melanocyte destruction. 
- **Myasthenia gravis** - case series have reported benefit as an adjunct to cholinesterase inhibitors, though formal approval is lacking. 
- **Certain hematologic disorders (e.g., immune thrombocytopenia)** - azathioprine is sometimes employed when first-line therapies fail, with evidence of modest platelet count improvement. 

These applications remain off-label; their safety and efficacy have not been formally evaluated by regulatory agencies. Use should only occur under direct supervision of a qualified healthcare professional.

## Storage & Handling

- Store tablets at room temperature (20-25 °C / 68-77 °F) away from excess heat, moisture, and direct sunlight. 
- Keep the container tightly closed and out of reach of children. 
- Do not use tablets past the printed expiration date. 
- Dispose of unused medication according to local pharmacy take-back programs or established hazardous waste guidelines.

## Frequently Asked Questions

**Practical Use & Lifestyle**

- **Can I travel internationally with Imuran?** 
 Yes, but carry a copy of the prescription and a letter from your physician, as some countries require documentation for immunosuppressants.

- **Should I adjust the timing of Imuran around meals?** 
 Taking the tablet with food or milk can lessen stomach upset; timing does not otherwise affect absorption.

**Product & Formulation Details**

- **What do Imuran tablets look like?** 
 Imuran tablets are round, film-coated, and debossed with “IMURAN” on one side; strength is indicated by a colored score line.

- **Are there any inactive ingredients I should be aware of?** 
 Common excipients include lactose, magnesium stearate, and hydroxypropyl cellulose; patients with specific allergies should review the full ingredient list.

**Regulatory & Safety Nuances**

- **Will Imuran appear on a routine drug test?** 
 Standard employment drug panels do not test for azathioprine; however, specialized medical testing can detect its metabolites if specifically requested.

- **Is Imuran safe for athletes subject to anti-doping regulations?** 
 Azathioprine is not listed as a prohibited substance by major sports agencies, but athletes should disclose its use to the relevant authority.

**Scientific & Clinical Curiosity**

- **What was the original purpose of developing azathioprine?** 
 It was first synthesized as an anti-cancer agent in the 195s before its potent immunosuppressive properties were recognized.

- **How does TPMT testing influence dosing?** 
 Patients with low or absent TPMT activity are at high risk for severe myelosuppression; they require a drastically reduced dose or alternative therapy.

## Glossary

**Immunosuppressant** 
: A drug that reduces the activity of the immune system, decreasing the likelihood of organ rejection or autoimmune attacks.

**Thiopurine Methyltransferase (TPMT)** 
: An enzyme that metabolizes azathioprine; genetic variations affect drug tolerance and dosing requirements.

**Bioequivalence** 
: The condition wherein a generic drug demonstrates the same rate and extent of absorption as the reference brand product.

## Disclaimer

The information provided about **Imuran** is for general knowledge only. It does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. [our online pharmacy](https://liabilis.com/order-imuran-online-en.html) offers access to **Imuran** for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.