--- title: Buy Generic Diane 35 2/0.035mg Pills description: Generic Diane 35 pills combine cyproterone and ethinylestradiol for acne and hormone regulation. Effective treatment from our secure pharmacy. type: product language: en url: https://liabilis.com/order-diane-35-online-en.html availability: in_stock shipping: - type: Standard Airmail price: 10.00 currency: USD area: Worldwide time: 14-21 days - type: Tracked Express price: 30.00 currency: USD area: Worldwide tracking: true time: 5-9 days price_min: 70.29 price_max: 160.54 currency: USD offers: - name: 2/0.035mg x 35 pills price: 70.29 - name: 2/0.035mg x 70 pills price: 106.39 - name: 2/0.035mg x 105 pills price: 144.99 - name: 2/0.035mg x 140 pills price: 160.54 --- # Buy Generic Diane 35 2/0.035mg Pills Diane 35 contains cyproterone acetate and ethinylestradiol, combining anti-androgen and estrogen components. It is used to treat severe acne and hirsutism in women, particularly when related to hormonal imbalances. This medication helps regulate androgen-related skin conditions. Our pharmacy offers Diane 35 in 2mg/0.035mg combination pills. ## Pricing and Options | Dosage | Pack Size | Price (USD) | Price Per Pill | Status | | :--- | :--- | :--- | :--- | :--- | | **2/0.035mg** | 35 pills | **$70.29** | $2.00 | In Stock | | **2/0.035mg** | 70 pills | **$106.39** | $1.52 | In Stock | | **2/0.035mg** | 105 pills | **$144.99** | $1.38 | In Stock | | **2/0.035mg** | 140 pills | **$160.54** | $1.15 | In Stock | [Buy Now](https://liabilis.com/order-diane-35-online-en.html) ## Introduction Diane 35 is the generic version of medications containing the active compounds cyproterone acetate and ethinylestradiol. It is supplied as an oral tablet (pill) with a fixed combination of 2 mg cyproterone acetate / .035 mg ethinylestradiol. The product belongs to the class of combined oral contraceptives (COCs) with anti-androgenic activity. In addition to contraception, it is prescribed for androgen-dependent skin conditions such as severe acne and hirsutism. --- ## Quick Reference Facts **Active Ingredient** : Cyproterone acetate and ethinylestradiol **Form** : pill 2/.035 mg **Primary Uses** : - Hormonal contraception - Treatment of severe acne - Management of hirsutism --- ## What is Diane 35? Diane 35 is a combined oral contraceptive that blends a progestogen (cyproterone acetate) with a synthetic estrogen (ethinylestradiol). The medication is classified as a combined hormonal contraceptive with anti-androgenic properties. It is manufactured by several licensed pharmaceutical companies and is distributed internationally under various brand names, including **Diane-35** and **Dianette**. As a generic product, Diane 35 provides the same therapeutic effect as its branded counterparts while offering a lower cost option. --- ## How Diane 35 Works Cyproterone acetate binds to androgen receptors, blocking the action of circulating testosterone and other androgens. This anti-androgenic effect reduces sebum production and hair follicle stimulation, which underlies its efficacy in acne and hirsutism. Ethinylestradiol activates estrogen receptors, stabilizing the endometrial lining and suppressing the mid-cycle luteinizing hormone (LH) surge, thereby preventing ovulation. The combined action also increases hepatic production of sex-hormone-binding globulin (SHBG), further lowering free androgen levels. After oral administration, both compounds are absorbed rapidly; cyproterone acetate undergoes hepatic metabolism via CYP3A4, while ethinylestradiol is metabolized primarily by CYP3A4 and conjugated for renal excretion. The contraceptive effect is maintained with daily dosing, and anti-androgenic benefits appear within several weeks of continuous use. --- ## Conditions Treated with Diane 35 - **Hormonal contraception** The suppression of ovulation, thickening of cervical mucus, and alteration of the endometrium provide reliable pregnancy prevention when taken correctly. - **Severe acne** By reducing circulating free androgens and sebum output, Diane 35 can markedly improve inflammatory and non-inflammatory lesions in women whose acne is androgen-driven. - **Hirsutism** The anti-androgenic component decreases terminal hair growth on the face, chest, and abdomen, offering cosmetic improvement for women with excess hair due to conditions such as polycystic ovary syndrome (PCOS). --- ## Is Diane 35 the Right Medication for You? Diane 35 is most suitable for women of reproductive age who require reliable contraception and have clinically significant androgen-related skin conditions. Ideal candidates are non-smoking women under 35 years, without a history of thromboembolic disease, and with normal liver function. It is particularly advantageous for patients who have not responded adequately to standard COCs lacking anti-androgenic activity. Contraindications include pregnancy, current or past venous thromboembolism, estrogen-dependent neoplasia (e.g., breast or endometrial cancer), uncontrolled hypertension, severe hepatic impairment, and known hypersensitivity to either component. Women who smoke heavily (>15 cigarettes per day) and are over 35 years should avoid this formulation because of an elevated risk of cardiovascular events. Clinicians may prefer alternative contraceptives for patients with migraine with aura, known clotting disorders, or a strong family history of thrombotic disease. --- ## Buying Diane 35 from [our online pharmacy](https://liabilis.com/order-diane-35-online-en.html) **Why Choose Our Service?** [our online pharmacy](https://liabilis.com/order-diane-35-online-en.html) offers a streamlined way to obtain Diane 35 when local pharmacies have limited stock or when price differences are prohibitive. By sourcing directly from licensed international distributors, we help patients maintain continuity of therapy without compromising quality. **Quality & Safety Assurance** We partner with licensed international pharmacies to ensure quality and authenticity. Every batch is verified against regulatory standards, and packaging includes tamper-evident seals. **Pricing & Access** Because Diane 35 is a generic formulation, the price is markedly lower than brand-name equivalents such as Diane-35 or Dianette. This cost advantage makes long-term treatment more affordable, especially for chronic skin conditions that require continuous therapy. **Discreet Delivery** Orders placed through our platform arrive in unmarked, secure packaging. Express delivery typically reaches most destinations within 7 days, while standard airmail takes approximately 3 weeks, allowing you to receive your medication privately and promptly. --- ## Use: Dosing, Missed Dose, Overdose - **Standard dosing** One tablet (2 mg cyproterone acetate / .035 mg ethinylestradiol) taken orally each day, preferably at the same time, for 21 consecutive days followed by a 7-day pill-free interval. - **Missed dose** If a tablet is missed and it has been ≤ 12 hours, take it as soon as remembered and continue with the next dose at the usual time. If more than 12 hours have passed, discard the missed tablet, take the next scheduled dose at the regular time, and use a backup method (e.g., condoms) for the next 48 hours. - **Overdose** In case of accidental overdose, seek immediate medical attention. Symptoms may include nausea, vomiting, breast tenderness, and dizziness. Supportive care is the mainstay of treatment. - **Practical precautions** - Take with water; food does not affect absorption. - Avoid excessive alcohol, which can increase the risk of hepatic strain and dizziness. - Do not operate heavy machinery if you feel dizzy or light-headed. --- ## Safety Information ### ⚠️ Who Should Not Take Diane 35 - Pregnant or breastfeeding women - Current or past venous thromboembolism (deep vein thrombosis, pulmonary embolism) - Known or suspected estrogen-dependent tumors (breast, endometrial, ovarian) - Uncontrolled hypertension (≥ 160/100 mm Hg) - Severe liver disease (e.g., hepatic cirrhosis, hepatitis) - Smokers > 15 cigarettes per day who are ≥ 35 years of age - History of migraine with aura ### Common Side Effects - Nausea and mild stomach upset (≈ 10-15 %) - Breast tenderness or enlargement (≈ 8-12 %) - Headache (≈ 7-10 %) - Weight gain or fluid retention (≈ 5-8 %) - Mood changes or mild depression (≈ 4-6 %) Most of these effects are transient and lessen after the first menstrual cycle. ### Serious Side Effects (Seek Immediate Medical Help) - Sudden onset of leg pain, swelling, or warmth (possible deep vein thrombosis) - Chest pain, shortness of breath, or coughing up blood (possible pulmonary embolism) - Severe abdominal pain with jaundice (possible hepatic tumor) - Unexplained bruising or prolonged bleeding (coagulopathy) - Visual disturbances or sudden severe headache (possible stroke) If any of these occur, discontinue Diane 35 and contact emergency services without delay. ### Drug & Food Interactions - **Enzyme inducers** (e.g., rifampicin, carbamazepine, phenytoin) may reduce contraceptive efficacy. - **Antifungal azoles** (ketoconazole, itraconazole) can increase ethinylestradiol levels, heightening clot risk. - **Antiretrovirals** (e.g., ritonavir) may alter hormone metabolism; close monitoring required. - **Anticoagulants** (warfarin) - combined oral contraceptives may increase INR; dose adjustment may be needed. - **St. John’s wort** - may diminish contraceptive effect through CYP3A4 induction. Always inform your healthcare provider of all medicines, supplements, and herbal products you are using. --- ## Off-Label and Investigational Uses of Diane 35 - **Polycystic ovary syndrome (PCOS) with hyperandrogenism** Clinical studies have shown that the anti-androgenic component can improve menstrual regularity and reduce acne in PCOS patients, although the formulation is not formally approved for this indication. - **Female pattern hair loss** Small case series suggest benefit from cyproterone acetate’s androgen-blocking effect, but evidence remains limited. - **Adjunct in gender-affirming hormone therapy for transgender women** Some endocrinology protocols incorporate cyproterone acetate for its anti-androgenic properties, yet this use is off-label and should be supervised by an experienced clinician. *Off-label use should only be considered under the direct supervision of a qualified healthcare provider.* --- ## Storage & Handling - Store tablets at **20-25 °C (68-77 °F)** in a dry place, protected from moisture and direct sunlight. - Keep the container tightly closed; do not freeze. - Expiry date is printed on the package; discard any tablets past this date. - Dispose of unused tablets according to local regulations, preferably via a pharmacy take-back program. --- ## Frequently Asked Questions **Practical Use & Lifestyle** - **Can I travel internationally with Diane 35?** Yes. Keep the medication in its original packaging with the prescription label (if required) and be aware of the importing regulations of your destination country. - **Does taking Diane 35 affect my ability to fly?** No specific restrictions exist. However, if you have a history of clotting disorders, discuss travel plans with your physician, as prolonged immobility can increase thrombotic risk. - **Is it safe to exercise while on Diane 35?** Regular physical activity is encouraged. If you experience unusual leg swelling or pain during or after exercise, seek medical evaluation promptly. **Product & Formulation Details** - **What do Diane 35 tablets look like?** Generic Diane 35 tablets are typically round, bicolored (often white and pink) with the dosage strength imprinted on one side. Appearance may vary slightly between manufacturers. - **Are there any inactive ingredients I should be aware of?** Common excipients include lactose, magnesium stearate, and cellulose. Patients with lactose intolerance should verify with the supplier, as trace amounts may be present. **Regulatory & Safety Nuances** - **Will Diane 35 appear on a standard drug test?** Standard workplace drug screens do not detect hormonal contraceptives. However, specialized tests for synthetic estrogens exist but are rarely used outside clinical research. - **Can I use Diane 35 while breastfeeding?** It is not recommended; estrogen-containing contraceptives can reduce milk production and may expose the infant to hormonal residues. - **Does smoking increase the risk of side effects?** Yes. Smoking, especially in women over 35, significantly raises the risk of venous thromboembolism and cardiovascular events when combined with estrogen-containing pills. **Scientific & Clinical Curiosity** - **How was cyproterone acetate discovered?** Cyproterone acetate was first synthesized in the 195s as a steroidal anti-androgen, later combined with ethinylestradiol to create a contraceptive with dual hormonal activity. - **What clinical trials supported the approval of Diane 35?** Large, multicenter Phase III trials demonstrated contraceptive efficacy comparable to other COCs and superior improvement in severe acne scores versus placebo. --- ## Glossary **Combined Oral Contraceptive (COC)** : A pill that contains both an estrogen and a progestogen to prevent pregnancy by inhibiting ovulation and altering cervical mucus. **Anti-androgen** : A substance that blocks the effects of male hormones (androgens) at receptor sites, reducing androgen-driven symptoms such as excess hair growth. **Venous Thromboembolism (VTE)** : A condition encompassing deep-vein thrombosis and pulmonary embolism, often associated with estrogen-containing medications. **Sex-Hormone-Binding Globulin (SHBG)** : A liver-produced protein that binds circulating sex hormones, reducing the amount of biologically active testosterone and estradiol. **CYP3A4** : A liver enzyme that metabolizes many drugs, including both components of Diane 35; inducers or inhibitors of this enzyme can affect drug levels. --- ## Disclaimer The information provided about **Diane 35** is for general knowledge only. It does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. [our online pharmacy](https://liabilis.com/order-diane-35-online-en.html) offers access to **Diane 35** for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.