--- title: Buy Dasatinib 50mg Bottle Online description: Dasatinib 50mg is a tyrosine kinase inhibitor for certain types of leukemia. Order this targeted cancer therapy from our reliable online pharmacy. type: product language: en url: https://liabilis.com/order-dasatinib-online-en.html availability: in_stock shipping: - type: Standard Airmail price: 10.00 currency: USD area: Worldwide time: 14-21 days - type: Tracked Express price: 30.00 currency: USD area: Worldwide tracking: true time: 5-9 days price_min: 189.99 price_max: 509.99 currency: USD offers: - name: 50mg x 1 bottle price: 189.99 - name: 50mg x 2 bottles price: 345.79 - name: 50mg x 3 bottles price: 509.99 --- # Buy Dasatinib 50mg Bottle Online Dasatinib is a tyrosine kinase inhibitor that targets multiple cancer-causing proteins, particularly used in treating certain types of leukemia including Philadelphia chromosome-positive cases. It works by blocking signals that promote cancer cell growth and division. This medication is prescribed for adults with specific hematologic malignancies who require targeted therapy. Our pharmacy provides Dasatinib in 50mg bottles from verified manufacturers. ## Pricing and Options | Dosage | Pack Size | Price (USD) | Price Per Pill | Status | | :--- | :--- | :--- | :--- | :--- | | **50mg** | 1 bottle | **$189.99** | $189.99 | In Stock | | **50mg** | 2 bottles | **$345.79** | $172.90 | In Stock | | **50mg** | 3 bottles | **$509.99** | $170.00 | In Stock | [Buy Now](https://liabilis.com/order-dasatinib-online-en.html) ## Introduction Dasatinib is a prescription-only medication used to treat specific blood cancers. It contains the active ingredient **Dasatinib** and is supplied as a bottle of 50 mg tablets. Classified as a potent tyrosine-kinase inhibitor, Dasatinib blocks signaling pathways that drive the growth of malignant cells. Its primary approved uses are chronic myeloid leukemia (CML) and Philadelphia-chromosome-positive acute lymphoblastic leukemia (Ph⁺ ALL). The drug is also investigated for other hematologic conditions, although those uses remain off-label. ## Quick Reference Facts **Active Ingredient** : Dasatinib **Form** : bottle - 50 mg tablets **Primary Uses** : • Chronic myeloid leukemia (CML) • Philadelphia-chromosome-positive acute lymphoblastic leukemia (Ph⁺ ALL) ## What is Dasatinib? Dasatinib is a small-molecule inhibitor that targets several tyrosine kinases, most notably BCR-ABL, SRC family kinases, c-KIT, and PDGFR. It belongs to the class of **tyrosine-kinase inhibitors (TKIs)**, a therapeutic group that interferes with intracellular signaling required for cancer cell proliferation. Dasatinib is the **generic version of medications containing the active compound Dasatinib**. Marketed under brand names such as **Sprycel**, the generic formulation is bio-equivalent and offers a lower-cost alternative while maintaining the same safety and efficacy profile. The drug is manufactured by several licensed pharmaceutical companies worldwide and is approved by major regulatory agencies, including the U.S. FDA and the European EMA. ## How Dasatinib Works Dasatinib binds to the ATP-binding pocket of targeted kinases, preventing phosphorylation of downstream proteins that normally trigger cell division and survival. By inhibiting BCR-ABL-a fusion protein created by the Philadelphia chromosome-Dasatinib halts the uncontrolled growth of leukemic cells in CML and Ph⁺ ALL. Its broader activity against SRC family kinases also disrupts additional pathways that cancer cells may exploit, providing a more comprehensive blockade than earlier TKIs. After oral administration, Dasatinib is rapidly absorbed; peak plasma concentrations occur within 1-2 hours. The drug is metabolized primarily by CYP3A4 and eliminated via feces, giving it a terminal half-life of approximately 3-5 hours, which supports once-daily dosing for most indications. ## Conditions Treated with Dasatinib - **Chronic Myeloid Leukemia (CML) - chronic phase** Dasatinib’s inhibition of BCR-ABL suppresses the malignant clone, leading to durable cytogenetic and molecular responses in patients who are resistant or intolerant to first-generation TKIs. - **Chronic Myeloid Leukemia - accelerated or blast phase** Higher daily doses (140 mg) are employed to achieve deeper kinase inhibition needed for more aggressive disease variants. - **Philadelphia-chromosome-positive Acute Lymphoblastic Leukemia (Ph⁺ ALL)** By targeting BCR-ABL and SRC kinases, Dasatinib enhances remission rates when combined with standard chemotherapy regimens. ## Is Dasatinib the Right Medication for You? Dasatinib is appropriate for adults diagnosed with CML or Ph⁺ ALL who meet the specific clinical criteria for TKI therapy. It is especially valuable for patients who have experienced resistance or intolerance to imatinib, the first-generation TKI. Suitable candidates are generally able to swallow tablets and have adequate liver function, as the drug is metabolized by CYP3A4. Contraindications include severe hepatic impairment, known hypersensitivity to Dasatinib, and concurrent use of strong CYP3A4 inhibitors (e.g., ketoconazole) that could raise drug levels to unsafe concentrations. Patients with a history of bleeding disorders or uncontrolled hypertension should be evaluated carefully, as Dasatinib can exacerbate these conditions. ## Buying Dasatinib from [our online pharmacy](https://liabilis.com/order-dasatinib-online-en.html) **Why Choose Our Service?** Accessing Dasatinib can be challenging due to cost and limited availability in some regions. [our online pharmacy](https://liabilis.com/order-dasatinib-online-en.html) streamlines the process, providing a reliable source for the generic 50 mg tablets at prices close to wholesale rates. **Quality & Safety Assurance** We partner with licensed international pharmacies to ensure quality and authenticity. Each shipment is verified against regulatory standards, guaranteeing that you receive the exact medication prescribed. **Pricing & Access** Because Dasatinib is offered as a generic, you benefit from significant cost savings compared with brand-name Sprycel. Our platform makes it possible to obtain the medication even when local pharmacies run out of stock. **Discreet Delivery** Orders are packed in neutral, unmarked packaging and dispatched with express delivery typically within 7 days, or via standard airmail in approximately 3 weeks. Your privacy is protected at every step. ## Use: Dosing, Missed Dose, Overdose - **Standard Dosing** • CML (chronic phase): 100 mg once daily. • CML (accelerated/blast phase): 140 mg once daily. • Ph⁺ ALL: 70 mg twice daily (or 140 mg once daily, depending on protocol). Dosage may be adjusted for renal or hepatic impairment. - **Missed Dose** If you forget a dose, take it as soon as you remember *provided* it is not within 6 hours of the next scheduled dose. Skip the missed tablet and resume the regular schedule; do not double-dose. - **Overdose** In the event of an apparent overdose, seek emergency medical attention immediately. Symptoms may include severe nausea, vomiting, low blood pressure, or bleeding. Supportive care and monitoring are the mainstays of treatment. - **Practical Precautions** Take Dasatinib with a full glass of water on an empty stomach (at least 1 hour before or 2 hours after a meal) to maximize absorption. Avoid alcohol and refrain from operating heavy machinery until you know how the drug affects you. ## Safety Information ### ⚠️ Who Should Not Take Dasatinib - Patients with known hypersensitivity to Dasatinib or any of its excipients. - Individuals with severe hepatic impairment (Child-Pugh C). - Those receiving strong CYP3A4 inhibitors (e.g., itraconazole, clarithromycin) unless dose adjustment is made under medical supervision. ### Common Side Effects - **Fluid retention** (edema, pleural effusion) - occurs in up to 30 % of patients; may require dose modification. - **Myelosuppression** (low blood counts) - routine blood monitoring is essential. - **Gastrointestinal discomfort** (nausea, diarrhea) - generally mild and transient. ### Serious Side Effects (Seek Immediate Medical Help) - **Severe bleeding** or hemorrhage - especially in patients on anticoagulants. - **Pulmonary arterial hypertension** - rare but potentially life-threatening; discontinue if diagnosed. - **Cardiac events** (QT prolongation, arrhythmia) - monitor ECG in high-risk individuals. ### Drug & Food Interactions - **CYP3A4 inhibitors** (ketoconazole, erythromycin) - increase Dasatinib plasma levels; dose reduction may be required. - **CYP3A4 inducers** (rifampin, carbamazepine) - decrease effectiveness; avoid concurrent use. - **Antacids containing aluminum or magnesium** - reduce absorption; separate administration by at least 2 hours. - **Warfarin** - may enhance anticoagulant effect; monitor INR closely. ## Off-Label and Investigational Uses of Dasatinib - **Myelofibrosis** - Small phase II studies suggest symptom improvement, though the drug is not approved for this indication. - **Solid Tumors (e.g., breast, prostate)** - Preclinical data show activity against SRC kinases; clinical trials are ongoing but results remain inconclusive. - **Chronic Graft-versus-Host Disease** - Early-phase research indicates potential benefit, but safety and efficacy are not yet established. Off-label use should only be considered under the direct supervision of a qualified healthcare provider. ## Storage & Handling - Store tablets at 15-30 °C (59-86 °F) in a dry place, protected from light. - Keep the bottle tightly closed and out of reach of children. - Discard any tablets that are discolored, cracked, or past the expiration date. - Retour safely according to local pharmaceutical waste guidelines. ## Frequently Asked Questions **Practical Use & Lifestyle** - **Can I travel internationally with Dasatinib tablets?** Yes, but carry a copy of the prescription and a letter from your physician. Keep the medication in its original labeled container to avoid customs issues. - **Does Dasatinib interact with caffeine?** No direct interaction has been documented. Nonetheless, excessive caffeine may exacerbate anxiety or palpitations, which some patients experience with TKIs. - **Should I avoid sunlight while taking Dasatinib?** Dasatinib does not increase photosensitivity, but patients often experience skin rashes; using sunscreen can help manage this symptom. **Product & Formulation Details** - **What do Dasatinib tablets look like?** The generic 50 mg tablets are typically round, white to off-white, and may be film-coated. Specific appearance can vary by manufacturer. - **Can the tablet be split or crushed?** Dasatinib tablets are not formulated for splitting; crushing may alter absorption and should be avoided unless a pharmacist advises otherwise. **Regulatory & Safety Nuances** - **Will Dasatinib show up on a standard drug test?** Routine employment drug screens do not target TKIs, so Dasatinib will not be detected in typical panels. - **Is Dasatinib safe for elderly patients?** Older adults may have increased risk of myelosuppression and cardiac events; dose adjustments and close monitoring are recommended. - **What are the import rules for Dasatinib in the United States?** Personal import of prescription medicines is allowed under FDA guidelines if the medication is for a serious condition and is not for commercial resale. A valid prescription is required. **Scientific & Clinical Curiosity** - **When was Dasatinib first approved?** The FDA granted approval for Dasatinib (Sprycel) in 2006 for CML after demonstrating superior efficacy over imatinib in clinical trials. - **How does Dasatinib differ from imatinib?** Dasatinib binds to a broader spectrum of kinase conformations, including both active and inactive BCR-ABL forms, giving it activity against some imatinib-resistant mutations. - **Are there any patents still covering Dasatinib?** Original patents have expired, allowing generic manufacturing. Some formulation-specific patents may still be in force, but the active compound itself is widely available as a generic. ## Glossary **Tyrosine-Kinase Inhibitor (TKI)** : A class of drugs that block enzymes (tyrosine kinases) responsible for signaling pathways that promote cancer cell growth. **BCR-ABL** : An abnormal fusion protein produced by the Philadelphia chromosome; it drives uncontrolled proliferation in CML and Ph⁺ ALL. **CYP3A4** : A liver enzyme that metabolizes many medications, including Dasatinib; inhibitors or inducers of this enzyme can alter drug levels. **Myelosuppression** : A reduction in bone-marrow activity leading to low blood cell counts, a common side effect of cytotoxic therapies. **Pleural Effusion** : Accumulation of fluid in the space surrounding the lungs, occasionally observed with Dasatinib therapy. ## Disclaimer The information provided about **Dasatinib** is intended for general educational purposes and does not substitute professional medical consultation. All therapeutic decisions, including any off-label applications, should be made under the guidance of a qualified healthcare provider. Readers are presumed to be responsible adults capable of making informed health choices. [our online pharmacy](https://liabilis.com/order-dasatinib-online-en.html) offers access to **Dasatinib** for individuals who may encounter limited availability through conventional pharmacies, insurance-based dispensing, or who seek cost-effective generic alternatives. Always discuss with your doctor before initiating, modifying, or stopping any medication.