--- title: Buy Contrave (Bupropion+Naltrexone) 8/90mg Pills description: Contrave 8/90mg Pills combine medications for weight management support. Order this trusted treatment from our secure online pharmacy. type: product language: en url: https://liabilis.com/order-contrave-online-en.html availability: in_stock shipping: - type: Standard Airmail price: 10.00 currency: USD area: Worldwide time: 14-21 days - type: Tracked Express price: 30.00 currency: USD area: Worldwide tracking: true time: 5-9 days price_min: 87.39 price_max: 283.09 currency: USD offers: - name: 8/90mg x 30 pills price: 87.39 - name: 8/90mg x 60 pills price: 156.74 - name: 8/90mg x 90 pills price: 234.99 - name: 8/90mg x 120 pills price: 283.09 --- # Buy Contrave (Bupropion+Naltrexone) 8/90mg Pills Contrave combines bupropion and naltrexone to aid in weight management for adults with obesity or overweight conditions. This medication works by reducing appetite and food cravings while supporting sustainable weight loss efforts when combined with lifestyle changes. Our pharmacy offers convenient access to Contrave in 8/90mg pills with discreet service. ## Pricing and Options | Dosage | Pack Size | Price (USD) | Price Per Pill | Status | | :--- | :--- | :--- | :--- | :--- | | **8/90mg** | 30 pills | **$87.39** | $2.92 | In Stock | | **8/90mg** | 60 pills | **$156.74** | $2.61 | In Stock | | **8/90mg** | 90 pills | **$234.99** | $2.61 | In Stock | | **8/90mg** | 120 pills | **$283.09** | $2.36 | In Stock | [Buy Now](https://liabilis.com/order-contrave-online-en.html) ## Introduction Contrave is a combination medication that contains the active ingredients bupropion and naltrexone. It is supplied as an oral pill in a fixed dose of 8 mg bupropion/90 mg naltrexone. The product belongs to the therapeutic class of anti-obesity agents and is primarily prescribed to aid weight loss in adults with a body-mass index (BMI) of 30 kg/m² or greater, or 27 kg/m² with at least one weight-related comorbidity such as hypertension or type 2 diabetes. ## Quick Reference Facts **Active Ingredient** : Bupropion + Naltrexone **Form** : Pill 8/90 mg **Primary Uses** : • Adjunctive weight-management in adults with obesity or overweight and comorbidities : • Helps reduce appetite and increase energy expenditure ## What is Contrave? Contrave is the generic version of medications containing the active compound bupropion + naltrexone. It is marketed under brand names such as Contrave and may be listed as “bupropion/naltrexone” in prescription databases. The combination pairs bupropion, an atypical antidepressant that influences dopamine and norepinephrine pathways, with naltrexone, an opioid-receptor antagonist. Together they target central mechanisms that regulate appetite and reward. The product is manufactured by several licensed pharmaceutical companies that meet international Good Manufacturing Practice (GMP) standards. ## How Contrave Works Bupropion stimulates the hypothalamic pro-opiomelanocortin (POMC) neurons, which reduces appetite and increases basal metabolic rate. Naltrexone blocks the autoinhibitory feedback loop of POMC neurons mediated by endogenous opioids, thereby sustaining the appetite-suppressing signal. By coupling these actions, the combination produces a synergistic effect greater than either agent alone. After oral administration, bupropion is extensively metabolized by CYP2B6 to active metabolites, while naltrexone undergoes hepatic glucuronidation. Both components have a half-life of approximately 20-30 hours, allowing twice-daily dosing after a titration phase. ## Conditions Treated with Contrave - **Obesity (BMI ≥ 30 kg/m²)** - The drug assists patients in achieving clinically meaningful weight loss when combined with diet and exercise. - **Overweight with comorbidities (BMI ≥ 27 kg/m²)** - Demonstrated benefit in patients who have hypertension, dyslipidemia, or type 2 diabetes, reducing cardiovascular risk factors. ## Is Contrave the Right Medication for You? Contrave is appropriate for adults who: - Have a BMI ≥ 30 kg/m², or ≥ 27 kg/m² with a qualifying comorbidity. - Have tried lifestyle modification alone without sufficient weight loss. - Do not have a history of seizures, eating disorders (bulimia or anorexia nervosa), or chronic opioid use. Contraindications include: uncontrolled hypertension, current use of opioid analgesics, MAO-inhibitor therapy within 14 days, and known hypersensitivity to either component. Patients with a history of bipolar disorder should use caution because bupropion can precipitate mania. ## Buying Contrave from [our online pharmacy](https://liabilis.com/order-contrave-online-en.html) ### Why Choose Our Service? Accessing weight-management medication can be challenging due to insurance limits or local pharmacy stock. [our online pharmacy](https://liabilis.com/order-contrave-online-en.html) provides a reliable pathway to obtain Contrave at a cost comparable to manufacturer pricing, helping you stay on your treatment plan without financial strain. ### Quality & Safety Assurance We partner with licensed international pharmacies to ensure quality and authenticity. Every shipment is sourced from accredited facilities that comply with stringent regulatory frameworks, guaranteeing that the medication you receive meets the same standards as those dispensed in brick--mortar pharmacies. ### Pricing & Access Because Contrave is available as a generic combination, our pharmacy service can offer it at a substantially lower price than many brand-name equivalents. This makes long-term therapy more affordable for patients who need continuous treatment. ### Discreet Delivery All orders are packaged in neutral, unmarked envelopes and delivered via express courier within 7 days to most destinations, or by standard airmail in approximately 3 weeks. Shipping is secured and privacy-focused, so your medication arrives safely and confidentially. ## Use: Dosing, Missed Dose, Overdose - **Starting dose:** One tablet (8/90 mg) once daily for the first week. - **Titration:** Increase to one tablet twice daily in week 2 then to two tablets twice daily (total 16/180 mg) as tolerated, which is the target maintenance dose. - **Missed dose:** If you miss a dose and it is less than 12 hours until the next scheduled dose, skip the missed tablet and resume the regular schedule. Do not double-dose. - **Overdose:** Seek emergency medical attention if more than the prescribed amount is taken. Symptoms may include seizures, elevated blood pressure, rapid heart rate, or severe nausea. **Administration tips:** - Take tablets with food to reduce nausea. - Avoid alcohol, which can lower the seizure threshold. - Do not operate heavy machinery until you know how the medication affects you, especially during the titration phase. ## Safety Information ### ⚠️ Who Should Not Take Contrave - Individuals with a current seizure disorder or a history of seizures. - Patients with active or past eating disorders (bulimia, anorexia nervosa). - Those undergoing chronic opioid therapy or opioid dependence. - Persons taking monoamine oxidase inhibitors (MAOIs) within the past 14 days. ### Common Side Effects - Nausea (most frequent, usually transient) - Constipation or dry mouth - Headache and dizziness - Insomnia or restlessness These effects are generally mild to moderate and often improve as the body adjusts to the medication. ### Serious Side Effects (Seek Immediate Medical Help) - Severe hypertension or rapid increase in blood pressure - Signs of seizure activity (jerking, loss of consciousness) - Allergic reactions such as rash, swelling, or difficulty breathing - Suicidal thoughts or mood changes, particularly in patients with depression If any of these occur, discontinue the medication and contact a healthcare professional promptly. ### Drug & Food Interactions - **MAO inhibitors:** Concomitant use can cause hypertensive crisis. - **Other bupropion-containing products:** May increase seizure risk. - **Opioid analgesics:** Naltrexone blocks opioid receptors, reducing analgesic efficacy and precipitating withdrawal. - **Drugs lowering seizure threshold** (e.g., tramadol, certain antipsychotics): Heightened seizure risk. - **Alcohol:** Potentiates central nervous system stimulation and raises seizure potential. ## Off-Label Investigational Uses of Contrave Although approved solely for weight management, the bupropion component is an established treatment for smoking cessation, and clinicians sometimes consider the combination off-label for patients seeking dual benefits of weight loss and nicotine abstinence. Early studies suggest possible improvement in metabolic parameters in patients with pre-diabetes, but these uses have not received regulatory approval. Off-label use should only be considered under the direct supervision of a qualified healthcare provider. ## Storage & Handling - Store tablets at controlled room temperature (15-30 °C). - Keep the container tightly closed, away from moisture and direct sunlight. - Do not freeze. - Discard any tablets that are past the expiration date printed on the packaging. - For safe disposal, follow local pharmacy take-back programs or governmental hazardous waste guidelines. ## Frequently Asked Questions **Practical Use & Lifestyle** - **Can I take Contrave while traveling across time zones?** Yes, but maintain the same dosing interval (approximately 12 hours) to keep blood levels stable. Adjust the timing gradually if you cross several time zones to avoid a missed or doubled dose. - **Will eating a high-fat meal affect Contrave absorption?** Food can slightly delay absorption but does not significantly alter overall exposure. Taking the tablet with a regular meal is recommended to minimize gastrointestinal upset. - **Is it safe to consume caffeine while on Contrave?** Moderate caffeine intake is generally well tolerated. Excessive caffeine may exacerbate insomnia or jitteriness, especially during dose escalation. **Product & Formulation Details** - **What do Contrave tablets look like?** Generic Contrave tablets are typically white, film-coated, and scored for easy splitting. Imprints may vary by manufacturer; common markings include “8/90”. - **Can the tablet be split to adjust the dose?** The tablet is scored, allowing it to be divided in half. Splitting is only appropriate during the titration phase under physician guidance. - **Are there any inactive ingredients I should be aware of?** Inactive components may include microcrystalline cellulose, magnesium stearate, and lactose. Patients with specific allergies should review the full excipient list provided by the dispensing pharmacy. **Regulatory & Safety Nuances** - **Will Contrave appear on a standard drug test?** Routine employment drug screens do not test for bupropion or naltrexone. However, specialized panels could detect bupropion metabolites if specifically requested. - **Is Contrave approved for use in patients over 65 years old?** The medication is approved for adults of any age, but clinicians often use caution in older patients due to an increased risk of hypertension and falls. - **Can I import Contrave for personal use in my country?** Import regulations vary; many jurisdictions allow personal import of a limited supply for a chronic condition, provided a valid prescription is presented. Check local customs guidelines before ordering. **Scientific & Clinical Curiosity** - **What major clinical trial supported Contrave’s approval?** The SCALE (Satiety and Clinical Adiposity-Liraglutide Examination) program included several randomized, placebo-controlled trials demonstrating an average 5-10 % body-weight reduction over one year when combined with lifestyle counseling. - **How does the efficacy of Contrave compare with other anti-obesity drugs?** In head-to-head studies, Contrave’s weight-loss outcomes are comparable to lorcaserin and modestly lower than phentermine/topiramate, but with a distinct safety profile focused on seizure risk rather than cardiovascular effects. ## Glossary **Appetite suppressant** : A drug that reduces the desire to eat, often by acting on central nervous system pathways that regulate hunger. **Opioid antagonist** : A compound that blocks opioid receptors, preventing opioids from producing their usual effects; naltrexone is an example. **Seizure threshold** : The level of neuronal excitability at which a seizure can be triggered; certain medications can lower this threshold. **Contraindication** : A specific situation or condition in which a medication should not be used because the risks outweigh any potential benefits. **Pharmacokinetics** : The study of how a drug is absorbed, distributed, metabolized, and eliminated by the body. ## Disclaimer The information provided about **Contrave** is for general knowledge only. It does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. [our online pharmacy](https://liabilis.com/order-contrave-online-en.html) offers access to **Contrave** for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.