--- title: Buy Colospa (Mebeverine) 135mg Pills Online description: Colospa (Mebeverine) 135mg Pills provide relief from IBS symptoms and abdominal cramps. Order this trusted treatment from our secure online pharmacy. type: product language: en url: https://liabilis.com/order-colospa-online-en.html availability: in_stock shipping: - type: Standard Airmail price: 10.00 currency: USD area: Worldwide time: 14-21 days - type: Tracked Express price: 30.00 currency: USD area: Worldwide tracking: true time: 5-9 days price_min: 29.99 price_max: 162.99 currency: USD offers: - name: 135mg x 30 pills price: 29.99 - name: 135mg x 60 pills price: 55.44 - name: 135mg x 90 pills price: 73.26 - name: 135mg x 120 pills price: 84.99 - name: 135mg x 240 pills price: 162.99 --- # Buy Colospa (Mebeverine) 135mg Pills Online Colospa contains mebeverine and is specifically formulated to treat symptoms of irritable bowel syndrome, including abdominal pain, cramping, and bloating. This antispasmodic medication helps relax intestinal muscles, providing comfort for adults dealing with digestive discomfort. Our online pharmacy offers reliable access to Colospa in 135mg pills. ## Pricing and Options | Dosage | Pack Size | Price (USD) | Price Per Pill | Status | | :--- | :--- | :--- | :--- | :--- | | **135mg** | 30 pills | **$29.99** | $0.99 | In Stock | | **135mg** | 60 pills | **$55.44** | $0.92 | In Stock | | **135mg** | 90 pills | **$73.26** | $0.81 | In Stock | | **135mg** | 120 pills | **$84.99** | $0.71 | In Stock | | **135mg** | 240 pills | **$162.99** | $0.68 | In Stock | [Buy Now](https://liabilis.com/order-colospa-online-en.html) ## 1. Introduction Colospa is a oral pill that contains the antispasmodic agent mebeverine (135 mg). It belongs to the class of spasmolytics used to relieve smooth-muscle cramping of the gastrointestinal (GI) tract. The medication is indicated primarily for the treatment of irritable bowel syndrome (IBS) and other functional bowel disorders that cause abdominal pain, bloating, and irregular bowel movements. Colospa is supplied as a single-strength tablet, making dosing straightforward for most adults. ## 2. Quick Reference Facts ``` **Active Ingredient** : Mebeverine **Form** : Pill - 135 mg **Primary Uses** : • Irresponsible bowel syndrome (IBS) • Functional bowel disorders with abdominal cramping • Colonic spasm relief ``` ## 3. What is Colospa? Colospa is the generic version of medications containing the active compound mebeverine. Mebeverine is marketed under brand names such as **Colofac**, **Duspatal**, and **Mebeverin**. As a generic product, Colospa offers the same therapeutic effect as the branded equivalents while typically costing less. The formulation is a hard tablet designed for oral administration. While the original brand was developed by pharmaceutical companies in Europe, the generic version is produced by several licensed manufacturers that meet international quality standards. ## 4. How Colospa Works Mebeverine acts directly on the smooth muscle of the GI tract. It inhibits calcium influx into muscle cells, which reduces the contractile activity that leads to painful spasms. By stabilising the muscle membrane, the drug lessens the intensity and frequency of colonic contractions without significantly affecting normal peristalsis. The onset of relief is usually observed within 30 minutes after ingestion, and the effect can last up to 4-6 hours. Mebeverine is largely metabolised by the liver and eliminated in the urine as inactive metabolites, allowing for predictable dosing without the need for therapeutic drug monitoring. ## 5. Conditions Treated with Colospa - **Irritable Bowel Syndrome (IBS)** Functional bowel disturbances cause recurrent abdominal pain and altered stool consistency. By decreasing smooth-muscle hyper-activity, mebeverine reduces pain episodes and improves bowel regularity. - **Functional Bowel Disorders (FBD)** Conditions such as functional dyspepsia and spastic colon involve excessive colonic contractility. Colospa alleviates the spasmodic component, allowing patients to experience fewer urgency episodes and less bloating. - **Colonic Spasm after Gastrointestinal Surgery** Post-operative patients may develop transient spasm of the colon. A short course of mebeverine can help restore comfortable motility while the bowel recovers. ## 6. Is Colospa the Right Medication for You? Colospa is most appropriate for adults who have been diagnosed with IBS or related functional bowel disorders and who experience cramping pain that interferes with daily activities. It is especially useful when symptoms are not fully controlled by dietary modification or fibre supplementation. **When Colospa may unsuitable** - Known hypersensitivity to mebeverine or any tablet excipients. - Severe hepatic impairment, because metabolism is liver-dependent. - Pregnant or breastfeeding women should only use it if a physician explicitly recommends it, as safety data are limited. Patients with a history of cardiac arrhythmia or those taking medications that profoundly affect calcium channels should discuss potential interactions with their healthcare provider before starting therapy. ## 7. Buying Colospa from [our online pharmacy](https://liabilis.com/order-colospa-online-en.html) ### Why Choose Our Service? Accessing gastrointestinal medications can be difficult when local pharmacies have limited stock or high price marks. Our platform provides a convenient, cost-effective way to obtain Colospa, ensuring you receive the medication you need without unnecessary expense. ### Quality & Safety Assurance We partner with licensed international pharmacies to ensure quality and authenticity. Each shipment is sourced from manufacturers that follow Good Manufacturing Practice (GMP) guidelines and are inspected by regulatory authorities. ### Pricing & Access Because Colospa is a generic formulation, the price is markedly lower than that of brand-name mebeverine tablets. [our online pharmacy](https://liabilis.com/order-colospa-online-en.html) offers the medication at near-wholesale rates, making long-term therapy financially sustainable for most patients. ### Discreet Delivery Orders are packaged in plain, unmarked boxes and dispatched via reliable couriers. Express shipping typically delivers within 7 days, while standard airmail arrives in approximately 3 weeks. All personal data are encrypted and handled with strict confidentiality. ## 8. Use: Dosing, Missed Dose, Overdose - **Standard dosing** - One 135 mg tablet taken three times daily, preferably 30 minutes before meals. - **Missed dose** - If a dose is forgotten, take it as soon as you remember unless it is within 2 hours of the next scheduled dose; in that case, skip the missed tablet and resume the regular schedule. - **Overdose** - In the unlikely event of taking more than the prescribed amount, seek immediate medical attention or contact a poison-control centre. Symptoms may include severe dizziness, nausea, or fainting. - **Administration tips** - Swallow the tablet whole with a glass of water. Avoid concomitant alcohol, as it may increase the risk of dizziness. Operating heavy machinery should be delayed until you know how Colospa affects you. ## 9. Safety Information ### ⚠️ Who Should Not Take Colospa - Individuals with documented allergy to mebeverine or any tablet filler. - Patients with severe liver disease (e.g., Child-Pugh class C). - Pregnant or nursing women unless expressly advised by a physician. ### Common Side Effects - Mild headache (≈10 % of users) - Nausea or transient abdominal discomfort (≈5 %) - Dry mouth (≈3 %) These effects are generally self-limiting and do not require medical intervention unless they persist. ### Serious Side Effects (Seek Immediate Medical Help) - Severe allergic reaction: rash, itching, swelling of face or throat, difficulty breathing. - Rapid heart rhythm disturbances (palpitations, dizziness). - Persistent vomiting or severe abdominal pain. ### Drug & Food Interactions - **Calcium channel blockers** (e.g., amlodine): May potentiate the muscle-relaxant effect, leading to excessive GI hypomotility. - **Anticholinergic agents**: Combined use could intensify dry-mouth symptoms. - **Alcohol**: Increases the likelihood of dizziness and hypotension. - **Grapefruit juice**: No significant interaction reported, but limit excessive intake as a precaution. ## 10. Off-Label and Investigational Uses of Colospa Mebeverine has been investigated for relief of biliary colic and for reducing pelvic pain associated with endometriosis. Small clinical series suggest a modest benefit, but neither indication has received regulatory approval. Some gastroenterologists also prescribe mebeverine for chronic functional constipation when spasm contributes to symptomatology. Off-label use should only be undertaken under the direct supervision of a qualified healthcare provider, as the safety and efficacy profile for these conditions has not been formally established. ## 11. Storage & Handling - Store tablets at 20-25 °C (68-77 °F) in a dry place, away from direct sunlight. - Keep the container tightly closed to protect from moisture. - Do not use after the expiry date printed on the package. - Dispose of any unused tablets according to local pharmaceutical waste guidelines or return them to a pharmacy. ## 12. Frequently Asked Questions **Practical Use & Lifestyle** - **Can I travel internationally with Colospa?** Yes. Keep the medication in its original packaging with a copy of the prescription or a doctor’s note, as some countries require documentation for import of prescription-only drugs. - **Should I take Colospa with food or on an empty stomach?** The tablet is best absorbed when taken 30 minutes before meals; food does not significantly alter its effectiveness but may delay onset of relief. - **Is it safe to combine Colospa with a daily multivitamin?** Multivitamins contain no known ingredients that withbeverine, so co-administration is generally regarded as safe. **Product & Formulation Details** - **What does a Colospa tablet look like?** The tablet is round, white to off-white, and imprinted with “135” on one side. Appearance may vary slightly between manufacturers. - **Are there any inactive ingredients I should be aware of?** Common excipients include lactose, microcrystalline cellulose, and magnesium stearate. Patients with lactose intolerance should verify the specific formulation with the supplier. **Regulatory & Safety Nuances** - **Will a drug test detect mebeverine?** Mebeverine is not screened for in standard occupational or sports drug testing panels, as it is not a performance-enhancing or prohibited substance. - **Can elderly patients use Colospa safely?** Older adults may be more sensitive to dizziness; starting at a lower frequency (e.g., twice daily) under medical guidance is advisable. **Scientific & Clinical Curiosity** - **When was mebeverine first approved for clinical use?** Mebeverine received its first marketing authorisation in Europe in the early 197s and has been used for functional GI disorders for more than four decades. - **How does mebeverine differ from other antispasmodics like hyoscine?** Unlike anticholinergic agents such as hyoscine, mebeverine works primarily by stabilising calcium channels, resulting in fewer anticholinergic side effects (e.g., dry mouth, blurred vision). ## 13. Glossary **Antispasmodic** : A drug that reduces involuntary smooth-muscle contractions, alleviating cramping and pain. **Functional Bowel Disorder** : A group of conditions characterised by chronic GI symptoms without identifiable structural disease. **Calcium Channel Antagonist** : A compound that inhibits the flow of calcium ions into cells, decreasing muscle contractility. **Good Manufacturing Practice (GMP)** : International quality standards that ensure medicines are consistently produced and controlled. ## 14. Disclaimer The information presented about **Colospa** is intended for general educational purposes and does not replace professional medical consultation. All therapeutic decisions, including those concerning off-label applications, should be undertaken under the guidance of a qualified healthcare practitioner. Readers are presumed to be responsible adults capable of making informed health choices. Our pharmacy service provides access to **Colospa** for individuals who may encounter limited availability through conventional pharmacies, insurance-based dispensing channels, or who are seeking cost-effective generic alternatives. Prior to initiating, modifying, or discontinuing any medication, it is essential to discuss the plan with a physician.