--- title: Buy Azulfidine (Sulfasalazine) 500mg Pills description: Azulfidine (Sulfasalazine) treats ulcerative colitis and rheumatoid arthritis. Order 500mg pills from our trusted online pharmacy for effective inflammatory condition management. type: product language: en url: https://liabilis.com/order-azulfidine-online-en.html availability: in_stock shipping: - type: Standard Airmail price: 10.00 currency: USD area: Worldwide time: 14-21 days - type: Tracked Express price: 30.00 currency: USD area: Worldwide tracking: true time: 5-9 days price_min: 58.99 price_max: 365.74 currency: USD offers: - name: 500mg x 30 pills price: 58.99 - name: 500mg x 60 pills price: 83.82 - name: 500mg x 90 pills price: 112.86 - name: 500mg x 120 pills price: 160.99 - name: 500mg x 180 pills price: 219.99 - name: 500mg x 270 pills price: 284.99 - name: 500mg x 360 pills price: 365.74 --- # Buy Azulfidine (Sulfasalazine) 500mg Pills Azulfidine contains the active ingredient Sulfasalazine, originally developed by Pharmacia. This medication treats ulcerative colitis and rheumatoid arthritis by reducing inflammation in the colon and joints. It works through anti-inflammatory and immunomodulatory effects. It is designed for adults managing chronic inflammatory conditions. Our pharmacy offers convenient access to Azulfidine in 500mg tablets for reliable treatment of inflammatory disorders. ## Pricing and Options | Dosage | Pack Size | Price (USD) | Price Per Pill | Status | | :--- | :--- | :--- | :--- | :--- | | **500mg** | 30 pills | **$58.99** | $1.95 | In Stock | | **500mg** | 60 pills | **$83.82** | $1.40 | In Stock | | **500mg** | 90 pills | **$112.86** | $1.25 | In Stock | | **500mg** | 120 pills | **$160.99** | $1.34 | In Stock | | **500mg** | 180 pills | **$219.99** | $1.22 | In Stock | | **500mg** | 270 pills | **$284.99** | $1.05 | In Stock | | **500mg** | 360 pills | **$365.74** | $1.02 | In Stock | [Buy Now](https://liabilis.com/order-azulfidine-online-en.html) ## Introduction Azulfidine is a prescription medication that contains the active ingredient sulfasalazine. It is supplied as a 500 mg oral pill and belongs to the class of disease-modifying anti-rheumatic drugs (DMARDs). Sulfasalazine is primarily used to reduce inflammation and control immune activity in chronic autoimmune disorders. In addition to its main indication for inflammatory bowel disease, the drug is approved for certain rheumatologic conditions. --- ## Quick Reference Facts **Active Ingredient** : Sulfasalazine **Form** : Pill - 500 mg **Primary Uses** : • Ulcerative colitis • Crohn’s disease (moderate to severe) • Rheumatoid arthritis --- ## What is Azulfidine? Azulfidine is the generic version of medications that contain the active compound sulfonyl-azo-based sulfasalazine. It is marketed worldwide under several brand names, including Salazopyrin, Salofalk, and others. The drug was first introduced in the 195s and has since become a cornerstone therapy for certain inflammatory and autoimmune diseases. As a generic product, Azulfidine is required to demonstrate bioequivalence to its branded counterparts, ensuring the same therapeutic effect at a lower cost. --- ## How Azulfidine Works Sulfasalazine is a pro-drug composed of 5-aminosalicylic acid (5-ASA) linked to sulfapyridine. After oral administration, gut bacteria cleave the bond, releasing both components. * **5-ASA** acts locally in the gastrointestinal tract to inhibit cyclooxygenase and lipoxygenase pathways, reducing prostaglandin and leukotriene synthesis. This anti-inflammatory action dampens mucosal irritation in ulcerative colitis and Crohn’s disease. * **Sulfapyridine** is absorbed systemically and exerts immunomodulatory effects by interfering with T-cell activation and cytokine production, which helps control rheumatoid arthritis and other systemic inflammatory conditions. The dual mechanism provides both local gut relief and systemic immune regulation. Onset of symptom improvement can be seen within 2-4 weeks, although full therapeutic benefit may require several months of continuous therapy. Sulfasalazine is metabolized by hepatic aldehyde dehydrogenase and eliminated primarily via the kidneys; dose adjustments are necessary in renal impairment to avoid accumulation. --- ## Conditions Treated with Azulfidine - **Ulcerative Colitis** - Sulfasalazine reduces colonic inflammation, leading to fewer bowel movements, less bleeding, and mucosal healing. - **Crohn’s Disease (Moderate to Severe)** - The drug suppresses intestinal inflammation when other agents are insufficient, improving abdominal pain and weight loss. - **Rheumatoid Arthritis** - By modulating immune pathways, Azulfidine lessens joint swelling, pain, and the progressive destruction of cartilage and bone. - **Ankylosing Spondylitis** - Though not a first-line therapy, sulfasalazine can provide modest relief of peripheral joint symptoms in this axial spondyloarthropathy. - **Pouchitis** - In patients with an ileal pouch-anal anastomosis, the medication helps control inflammation of the pouch lining. Each indication is supported by regulatory approval from agencies such as the U.S. FDA and the European Medicines Agency, reflecting robust clinical trial data. --- ## Is Azulfidine the Right Medication for You? Azulfidine is suitable for adults with confirmed ulcerative colitis, Crohn’s disease, or rheumatoid arthritis who require a disease-modifying approach. It is especially beneficial for patients who have not achieved adequate control with non-steroidal anti-inflammatory drugs (NSAIDs) or who seek a steroid-sparing option. The medication is contraindicated in individuals with a known hypersensitivity to sulfonamides, sulfapyridine, or any component of the formulation. Patients with severe hepatic or renal impairment should avoid use or be closely monitored due to altered metabolism and excretion. Pregnant or breastfeeding women must discuss risks with their provider, as sulfasalazine crosses the placenta and is excreted in breast milk. Overall, Azulfidine is recommended when the therapeutic goal is long-term control of inflammation rather than short-term symptom relief. --- ## Buying Azulfidine from [our online pharmacy](https://liabilis.com/order-azulfidine-online-en.html) ### Why Choose Our Service? Accessing specialty medications can be challenging due to cost, insurance limitations, or geographic availability. Our platform offers a reliable alternative for patients seeking affordable, high-quality treatment options. ### Quality & Safety Assurance We partner with licensed international pharmacies to ensure quality and authenticity. Every batch of Azulfidine is verified against regulatory standards before dispatch. ### Pricing & Access Because Azulfidine is a generic formulation, it is typically priced well below brand-name equivalents such as Salazopyrin or Salofalk. Our pricing reflects near-manufacturer cost, helping you manage chronic therapy without financial strain. ### Discreet Delivery Orders are packaged in plain, unmarked boxes and shipped via express or standard airmail, usually arriving within 7 days (express) or approximately 3 weeks (standard). Your privacy is protected at every step. By choosing our pharmacy service, you gain a cost-effective, secure, and convenient route to obtain Azulfidine when traditional channels fall short. --- ## Use: Dosing, Missed Dose, Overdose - **Standard Dosing** - The typical adult regimen starts with 500 mg taken twice daily. Depending on disease severity and response, clinicians may increase the dose up to 1 g three times daily, not exceeding 3 g per day. Doses are individualized and should follow your prescriber’s instructions. - **Missed Dose** - If you realize a dose was missed within 4 hours, take it as soon as you remember. If it is almost time for the next dose, skip the missed one and resume your regular schedule. Do not double-dose. - **Overdose** - Symptoms may include nausea, vomiting, rash, or dizziness. Seek immediate medical attention or contact a poison control center. Prompt evaluation is essential to manage potential toxicity. - **Practical Tips** - Take Azulfidine with food to lessen gastrointestinal upset. Avoid alcohol, as it can increase the risk of liver irritation. Do not operate heavy machinery until you know how the medication affects you. --- ## Safety Information ### ⚠️ Who Should Not Take Azulfidine - Patients with a documented sulfonamide allergy. - Individuals with severe hepatic disease (e.g., cirrhosis) or renal failure (creine clearance < 30 mL/min) unless dose-adjusted. - Pregnant women in the first trimester without medical supervision; the drug is classified as Category C. - Children under 18 years unless prescribed by a pediatric rheumatologist or gastroenterologist. ### Common Side Effects - Nausea, abdominal discomfort, and loss of appetite (usually mild and transient). - Headache or dizziness. - Rash or mild photosensitivity. - Elevated liver enzymes; routine monitoring is advised. Most adverse effects are manageable with dose adjustment or symptomatic treatment. ### Serious Side Effects (Seek Immediate Medical Help) - Severe skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis. - Hematologic abnormalities: agranulocytosis, aplastic anemia, or thrombocytopenia. - Hepatotoxicity indicated by jaundice, dark urine, or right-upper-quadrant pain. - Acute interstitial nephritis presenting with flank pain and reduced urine output. If any of these occur, discontinue the medication and obtain emergency care. ### Drug & Food Interactions - **farin** - Sulfasalazine can potentiate anticoagulant effects; monitor INR closely. - **Methotrexate** - Combined use may increase hepatotoxic risk; liver function tests are recommended. - **Live Vaccines** - Immunosuppression may reduce vaccine efficacy; avoid during therapy. - **Folate-containing Foods/Supplements** - Sulfasalazine interferes with folate absorption; supplemental folic acid (1 mg daily) is often prescribed to prevent deficiency-related anemia. - **Alcohol** - Increases liver stress; limit intake. --- ## Off-Label and Investigational Uses of Azulfidine - **Psoriatic Arthritis** - Small open-label studies have reported improvement in joint swelling and skin lesions; larger trials are ongoing. - **Behçet’s Disease** - Sulfasalazine has been used to control mucocutaneous ulcers and ocular inflammation, though evidence remains limited. - **Dermatomyositis** - Some clinicians employ the drug for its immunomodulatory properties when conventional agents are contraindicated. These applications are not approved by major regulatory bodies. Off-label use should only be considered under the direct supervision of a qualified healthcare provider. --- ## Storage & Handling - Store at 20-25 °C (68-77 °F) in a dry place away from direct sunlight. - Keep the bottle tightly closed to protect tablets from moisture. - Do not freeze; excess heat may degrade the active ingredient. - Dispose of unused medication according to local pharmacy guidelines or by returning to a certified disposal program. --- ## Frequently Asked Questions **Practical Use & Lifestyle** - **Can I travel internationally with Azulfidine?** Yes, but carry the medication in its original labelled container and bring a copy of your prescription. Some countries require proof of medical necessity for chronic drugs. - **Should I take Azulfidine at a specific time of day?** It is usually taken twice daily, roughly 12 hours apart, with meals to reduce stomach upset. Consistency helps maintain stable blood levels. - **Will sunlight affect my tablets?** Sulfasalazine tablets are stable under normal indoor lighting, but prolonged exposure to direct sunlight can degrade potency. Keep them in a shaded area. **Product & Formulation Details** - **What do Azulfidine tablets look like?** They are round, white tablets embossed with “500 mg” on one side. Appearance may vary slightly between manufacturers, but the imprint is consistent. - **Are there any inactive ingredients I should be aware of?** Common excipients include lactose, povidone, and magnesium stearate. Patients with lactose intolerance should review their tolerance with a pharmacist. **Regulatory & Safety Nuances** - **Will Azulfidine show up on a drug test for athletes?** The drug does not contain prohibited performance-enhancing substances, but some sports agencies test for sulfonamide compounds. Verify with your governing body if you compete at a high level. - **Is a prescription required to import Azulfidine for personal use?** Many jurisdictions allow import of a 30-day supply with a valid prescription from a licensed prescriber. Check your country’s customs regulations before ordering. **Scientific & Clinical Curiosity** - **What major trials established Azulfidine’s efficacy?** Large, double-blind, placebo-controlled studies in the 197s and 198s demonstrated significant reductions in Crohn’s disease activity indices and rheumatoid arthritis DAS28 scores. - **How does sulfasalazine compare with newer biologics?** Sulfasalazine is less costly and orally administered, but biologics often provide faster and more pronounced disease control. Choice depends on disease severity, comorbidities, and patient preference. --- ## Glossary **Disease-Modifying Anti-Rheumatic Drug (DMARD)** : A class of medications that slow the progression of autoimmune diseases rather than merely relieving symptoms. **Pro-drug** : An inactive compound that is metabolized in the body to produce an active therapeutic agent. **Bioequivalence** : Demonstration that a generic product delivers the same amount of active ingredient into the bloodstream as the branded reference, under similar conditions. **Stevens-Johnson Syndrome** : A rare, life-threatening skin reaction characterized by widespread blistering and mucosal involvement. **Folate Deficiency** : A lack of vitamin B9, which can cause anemia and elevate homocysteine levels; sulfasalazine can impair folate absorption. --- ## The information presented about **Azulfidine** is intended for general educational purposes only and does not replace professional medical consultation. All therapeutic decisions, including those concerning off-label applications, should be made under the guidance of a qualified healthcare provider. Readers are presumed to be responsible adults capable of making informed health choices. [our online pharmacy](https://liabilis.com/order-azulfidine-online-en.html) provides access to **Azulfidine** for individuals who may encounter limited availability through traditional channels, insurance-based dispensaries, or who seek affordable generic alternatives. Always discuss any medication changes with your physician before initiating, modifying, or discontinuing treatment.