---
title: Buy Acyclovir Cream 5% 5g and 10g Tubes Online
description: Acyclovir Cream 5% treats cold sores and herpes infections topically. Order this antiviral cream from our secure online pharmacy.
type: product
language: en 
url: https://liabilis.com/order-acyclovir_cream-online-en.html
availability: in_stock
shipping:
  - type: Standard Airmail
    price: 10.00
    currency: USD
    area: Worldwide
    time: 14-21 days
  - type: Tracked Express
    price: 30.00
    currency: USD
    area: Worldwide
    tracking: true
    time: 5-9 days
price_min: 7.99
price_max: 33.99
currency: USD
offers:
  - name: 5g x 1 tube
    price: 7.99
  - name: 5g x 3 tubes
    price: 20.99
  - name: 5g x 5 tubes
    price: 33.99
  - name: 10g x 1 tube
    price: 10.99
  - name: 10g x 3 tubes
    price: 29.99
---

# Buy Acyclovir Cream 5% 5g and 10g Tubes Online

Acyclovir Cream 5% is a topical antiviral treatment that targets herpes simplex virus infections, particularly cold sores around the mouth and face. This cream formulation works by preventing the virus from multiplying and spreading to healthy cells, helping to reduce healing time and symptom severity. It is designed for adult use at the first sign of a cold sore outbreak. Our pharmacy provides Acyclovir Cream in both 5g and 10g tube sizes.

## Pricing and Options

| Dosage | Pack Size | Price (USD) | Price Per Pill | Status |
| :--- | :--- | :--- | :--- | :--- |
| **5g** | 1 tube | **$7.99** | $7.99 | In Stock |
| **5g** | 3 tubes | **$20.99** | $7.00 | In Stock |
| **5g** | 5 tubes | **$33.99** | $6.80 | In Stock |
| **10g** | 1 tube | **$10.99** | $10.99 | In Stock |
| **10g** | 3 tubes | **$29.99** | $10.00 | In Stock |


[Buy Now](https://liabilis.com/order-acyclovir_cream-online-en.html)

## 1. Introduction 
Acyclovir cream 5% is a topical antiviral medication used to treat external skin infections caused by the herpes simplex virus (HSV). The active ingredient is acyclovir, delivered in a tube of either 5 g or 10 g. As a generic product, it belongs to the class of nucleoside analog antivirals. The cream is approved for the local treatment of recurrent herpes labialis (cold sores) and genital herpes lesions. 

## 2. Quick Reference Facts 

**Active Ingredient** 
: Acyclovir 

**Form** 
: tube 5 g | 10 g, 5 % cream 

**Primary Uses** 
: Treatment of recurrent HSV-1 lesions (cold sores) and HSV-2 lesions (genital herpes) on external skin 

## 3. What is Acyclovir cream 5%? 
Acyclovir cream 5% is the generic version of medications containing the active compound acyclovir. It is marketed under brand names such as Zovirax and Zovirax Cream, and it represents the generic equivalent of those branded products. The formulation is a white to off-white cream intended for topical application to affected skin. Development of acyclovir began in the 197s, and the topical preparation received regulatory approval in the early 199s for localized HSV infections. 

## 4. How Acyclovir cream 5% Works 
Acyclovir is a nucleoside analogue that mimics the natural nucleoside guanosine. After entering a virus-infected cell, viral thymidine kinase phosphorylates acyclovir to acyclovir monophosphate, which is then converted by cellular enzymes to the active triphosphate form. Acyclovir triphosphate competes with deoxyguanosine triphosphate for incorporation into viral DNA, causing premature chain termination and halting viral replication. Because the activation step relies on viral thymidine kinase, the drug preferentially affects infected cells while sparing healthy tissue. When applied topically, the concentration at the lesion site is sufficient to suppress viral DNA synthesis, leading to faster lesion healing and reduced viral shedding. The drug is minimally absorbed systemically, so systemic exposure and related adverse effects are uncommon. 

## 5. Conditions Treated with Acyclovir cream 5% 

- **Recurrent herpes labialis (cold sores)** - The cream reduces lesion duration, pain, and viral shedding by inhibiting HSV-1 replication at the site of the sore. 
- **Genital herpes (HSV-2) lesions** - Applied to external genital lesions, it limits viral spread, accelerates crust formation, and eases discomfort. 

## 6. Is Acyclovir cream 5% the Right Medication for You? 

**Suitable patients** 
- Adults with a confirmed history of recurrent HSV-1 or HSV-2 lesions on skin or mucocutaneous surfaces. 
- Individuals who prefer a non-systemic option to avoid oral antiviral exposure. 

**Clinical scenarios favoring use** 
- Early treatment (within 48 hours of lesion onset) to achieve maximal reduction in healing time. 
- Patients with mild to moderate lesions that are confined to the epidermis and do not require systemic therapy. 

**Contraindications and cautions** 
- Known hypersensitivity to acyclovir, valacyclovir, or any cream excipients. 
- Extensive ulcerated or deep lesions where systemic therapy is indicated. 
- Neonates, infants, or immunocompromised patients with severe HSV disease; topical therapy alone may be insufficient. 

## 7. Buying Acyclovir cream 5% from [our online pharmacy](https://liabilis.com/order-acyclovir_cream-online-en.html) 

### Why Choose Our Service? 
Accessing antiviral cream can be challenging when local pharmacies face stock shortages or when insurance coverage drives up out-of-pocket costs. Our platform offers a straightforward way to obtain the generic formulation at a price close to the manufacturer’s cost, helping you stay on schedule with your treatment plan. 

### Quality & Safety Assurance 
We partner with licensed international pharmacies to ensure quality and authenticity. All batches are sourced from reputable manufacturers that comply with Good Manufacturing Practices and are inspected by regulatory agencies. 

### Pricing & Access 
The generic nature of Acyclovir cream 5% provides a clear cost advantage over brand-name equivalents such as Zovirax. By ordering through our pharmacy service you benefit from reduced pricing while receiving the same therapeutic strength and concentration. 

### Discreet Delivery 
Orders are packaged in unbranded, tamper-evident envelopes and shipped with express delivery typically within 7 days, or via standard airmail in approximately 3 weeks. Your privacy is protected at every step, from checkout to doorstep. 

## 8. Use: Dosing, Missed Dose, Overdose 

- **Standard dosing for cold sores** - Apply a thin layer to the affected area five times daily (approximately every 4 hours) for four consecutive days. 
- **Standard dosing for genital herpes** - Apply the cream five times daily for ten days. 
- **Missed dose** - If a scheduled application is forgotten, apply it as soon as remembered unless the next dose is less than two hours away; in that case, skip the missed dose and resume the regular schedule. Do not double the dose. 
- **Overdose** - Because systemic absorption is minimal, toxicity from topical overdose is rare. If a large amount is applied inadvertently, rinse the area with water and seek medical advice if local irritation or systemic symptoms (e.g., nausea, dizziness) develop. 

**Practical precautions** 
- Apply to clean, dry skin; avoid contact with eyes, mouth, or open wounds unrelated to the HSV lesion. 
- Do not cover the treated area with occlusive dressings unless directed by a clinician. 
- Alcohol consumption does not affect topical efficacy, but avoid operating heavy machinery if the cream causes significant local irritation. 

## 9. Safety Information 

### ⚠️ Who Should Not Take Acyclovir cream 5% 

- Individuals with a documented allergy to acyclovir, valacyclovir, or any component of the cream base. 
- Patients with extensive, deep ulcerations where systemic antiviral therapy is indicated. 

### Common Side Effects 

- Mild burning, stinging, or itching at the application site (occurs in up to 10 % of users). 
- Redness or mild dermatitis localized to the treated area. 
These reactions are usually transient and resolve without medical intervention. 

### Serious Side Effects (Seek Immediate Medical Help) 

- Signs of a severe allergic reaction such as swelling of the face, lips, tongue, or throat, difficulty breathing, or widespread rash. 
- Persistent severe pain, ulceration, or secondary bacterial infection at the site of application. 

### Drug & Food Interactions 

- Topical acyclovir has negligible systemic absorption, so clinically significant drug-drug interactions are rare. 
- Caution is advised when using other topical agents (e.g., corticosteroid creams) on the same area, as they may alter skin permeability. 

## 10. Off-Label and Investigational Uses of Acyclovir cream 5% 

- **Prophylaxis in immunocompromised patients** - Small studies have evaluated topical acyclovir to prevent recurrent HSV lesions in transplant recipients and patients receiving chemotherapy. 
- **Herpetic keratitis adjunct** - Occasionally applied around the ocular margin in conjunction with systemic therapy for HSV eye infections, though evidence is limited. 

These applications have not received formal regulatory approval. Off-label use should only be considered under the direct supervision of a qualified healthcare provider. 

## 11. Storage & Handling 

- Store the tube at ≤ 30 °C (86 °F); avoid exposure to direct sunlight or extreme heat. 
- Keep the container tightly closed when not in use to maintain stability. 
- Do not use after the expiration date printed on the label. 
- Dispose of any remaining cream according to local pharmaceutical waste regulations or return to a pharmacy for safe disposal. 

## 12. Frequently Asked Questions 

**Practical Use & Lifestyle** 

- **Can I apply Acyclovir cream 5% while swimming or exercising?** 
 The cream should be applied to dry skin and allowed to absorb for a few minutes before exposure to water. Prolonged immersion may wash off the medication, reducing its effectiveness. 

- **Is it safe to use the cream during pregnancy?** 
 Topical acyclovir is classified as pregnancy category B by the FDA, indicating no evidence of risk in animal studies and a lack of well-controlled studies in pregnant women. Discuss use with your obstetric provider. 

- **Will the cream affect my ability to drive or operate machinery?** 
 Systemic absorption is minimal, so it does not impair cognitive or motor function. Local irritation might be uncomfortable, but it should not limit routine activities. 

**Product & Formulation Details** 

- **What ingredients besides acyclovir are in the cream?** 
 Inactive components typically include purified water, polyethylene glycol, cetyl alcohol, and carbomer. Exact excipient lists may vary by manufacturer. 

- **Does the cream have a distinct odor or taste?** 
 The formulation is largely odorless and non-tasteful; any faint smell is due to the base ingredients rather than the active drug. 

**Regulatory & Safety Nuances** 

- **Can Acyclovir cream 5% be purchased without a prescription?** 
 In many jurisdictions the topical product is available by prescription only. Our service complies with applicable regulations and may require a valid prescription for delivery. 

- **Will the cream show up on a drug test?** 
 Because systemic levels are extremely low, topical acyclovir does not appear in standard urine or blood drug screenings. 

**Scientific & Clinical Curiosity** 

- **How does the efficacy of topical acyclovir compare with oral antivirals?** 
 Oral acyclovir, valacyclovir, or famciclovir achieve higher systemic concentrations and are preferred for extensive lesions. Topical therapy is effective for early, localized recurrences and offers a lower systemic exposure profile. 

- **When was the 5 % cream formulation first approved?** 
 The 5 % topical formulation received FDA approval in 1992 for the treatment of recurrent herpes labialis and genital herpes lesions. 

## 13. Glossary 

**Thymidine kinase** 
: An enzyme produced by herpes viruses that phosphorylates acyclovir, initiating its activation inside infected cells. 

**Chain termination** 
: A process in which incorporation of a nucleoside analogue into viral DNA halts further elongation, preventing viral replication. 

**Good Manufacturing Practices (GMP)** 
: Regulatory standards that ensure pharmaceutical products are consistently produced and controlled according to quality criteria. 

**Systemic absorption** 
: The process by which a drug enters the bloodstream and distributes throughout the body, as opposed to remaining localized at the site of application. 

**Off-label use** 
: The prescription of a medication for an indication, dosage, or patient group that has not received official regulatory approval. 

## 14. Disclaimer 

The information provided about **Acyclovir cream 5%** is intended for general educational purposes and does not replace professional medical consultation. All treatment decisions, including those concerning off-label applications, must be made under the supervision of a qualified healthcare provider. Readers are presumed to be responsible adults capable of making informed health choices. [our online pharmacy](https://liabilis.com/order-acyclovir_cream-online-en.html) supplies Acyclovir cream 5% to individuals who may encounter limited availability through conventional pharmacies, insurance-based dispensing, or who are seeking cost-effective generic alternatives. Always discuss any medication changes with your doctor before initiating, altering, or discontinuing therapy.