--- title: Buy Generic Digoxin 0.25mg Pills description: Generic Digoxin 0.25mg pills for heart rhythm disorders and heart failure. Trusted cardiac medication from our secure pharmacy. type: product language: en url: https://liabilis.com/order-digoxin-online-en.html availability: in_stock shipping: - type: Standard Airmail price: 10.00 currency: USD area: Worldwide time: 14-21 days - type: Tracked Express price: 30.00 currency: USD area: Worldwide tracking: true time: 5-9 days price_min: 37.04 price_max: 139.99 currency: USD offers: - name: 0.25mg x 30 pills price: 37.04 - name: 0.25mg x 60 pills price: 47.49 - name: 0.25mg x 90 pills price: 58.99 - name: 0.25mg x 120 pills price: 52.24 - name: 0.25mg x 180 pills price: 70.29 - name: 0.25mg x 360 pills price: 139.99 --- # Buy Generic Digoxin 0.25mg Pills Digoxin is a cardiac glycoside medication that helps strengthen heart contractions and regulate heart rhythm. It treats conditions including atrial fibrillation and heart failure by improving cardiac efficiency. This well-established medication has been used for decades to manage various heart conditions. Our pharmacy provides digoxin in 0.25mg pills for reliable cardiac care. ## Pricing and Options | Dosage | Pack Size | Price (USD) | Price Per Pill | Status | | :--- | :--- | :--- | :--- | :--- | | **0.25mg** | 30 pills | **$37.04** | $1.23 | In Stock | | **0.25mg** | 60 pills | **$47.49** | $0.79 | In Stock | | **0.25mg** | 90 pills | **$58.99** | $0.66 | In Stock | | **0.25mg** | 120 pills | **$52.24** | $0.44 | In Stock | | **0.25mg** | 180 pills | **$70.29** | $0.39 | In Stock | | **0.25mg** | 360 pills | **$139.99** | $0.39 | In Stock | [Buy Now](https://liabilis.com/order-digoxin-online-en.html) ## 1. Introduction Digoxin is a cardiac glycoside used primarily to improve the strength and efficiency of heart contractions in adults with certain rhythm disorders and heart failure. The medication contains the active ingredient **Digoxin**, is supplied as a **pill** in a **.25 mg** strength, and belongs to the therapeutic class of **cardiac glycosides**. In addition to its main indication for atrial fibrillation and heart-failure management, digoxin is occasionally employed in other cardiac conditions under specialist supervision. --- ## 2. Quick Reference Facts ``` **Active Ingredient** : Digoxin **Form** : pill .25 mg **Primary Uses** : • Control of ventricular rate in atrial fibrillation • Symptom relief in chronic congestive heart failure ``` --- ## 3. What is Digoxin? Digoxin is the generic version of medications containing the active compound **Digoxin**. It is classified as a **cardiac glycoside**, a class of agents that increase cardiac contractility while slowing conduction through the atrioventricular (AV) node. Historically, digoxin was derived from the foxglove plant (*Digitalis lanata*); today it is synthesized and manufactured under strict pharmaceutical standards. In the United States and many other jurisdictions, the brand name **Lanoxin** is the most recognizable proprietary product, and digoxin is the bio-equivalent generic alternative. As a generic drug, digoxin is subject to rigorous FDA (or EMA) bio-equivalence testing, ensuring that its safety and efficacy match those of the branded formulation. This provides patients with a cost-effective option without compromising therapeutic outcomes. --- ## 4. How Digoxin Works Digoxin exerts its effect by inhibiting the sodium-potassium-ATPase enzyme on cardiac myocyte membranes. This inhibition leads to an increase in intracellular sodium, which indirectly raises intracellular calcium via the sodium-calcium exchanger. Higher calcium availability amplifies the contractile force of the heart (positive inotropy). Simultaneously, digoxin enhances vagal tone and slows conduction through the AV node, producing a **negative chronotropic** effect that helps control rapid heart rates in atrial fibrillation. The drug has a relatively narrow therapeutic window, meaning that blood concentrations must remain within a tight range (typically .5-2. ng/mL) to avoid toxicity. Digoxin is absorbed orally, reaches peak plasma levels within 1-3 hours, and is eliminated primarily by the kidneys; renal function therefore influences dosing and safety. --- ## 5. Conditions Treated with Digoxin - **Atrial Fibrillation (rate control)** Digoxin slows AV-node conduction, reducing ventricular response and easing symptoms such as palpitations and dyspnea. It is especially useful when patients have contraindications to beta-blockers or calcium-channel blockers. - **Chronic Congestive Heart Failure (NYHA Class II-III)** By increasing contractile force, digoxin improves cardiac output and may lessen hospital admissions for decompensation. Its benefit is most evident in patients with reduced ejection fraction who remain symptomatic despite optimal therapy. - **Atrial Flutter (rate control)** Similar to atrial fibrillation, digoxin can be employed to control ventricular rate when other agents are unsuitable. - **Certain Supraventricular Tachyarrhythmias** In selected cases, digoxin is part of a combination regimen to achieve rhythm stabilization, particularly in elderly patients with limited drug tolerance. --- ## 6. Is Digoxin the Right Medication for You? **Suitable patients** include adults with documented atrial fibrillation or flutter who require rate control, and those with symptomatic heart failure whose ejection fraction is ≤ 35 % and who have persistent symptoms despite ACE inhibitors, beta-blockers, or diuretics. **Clinical scenarios favoring digoxin** involve patients with concomitant chronic kidney disease (CKD) where dose adjustment can be precisely controlled, or individuals who cannot tolerate first-line rate-controlling agents due to bronchospasm, severe hypotension, or contraindicated drug interactions. **Contraindications**: severe sinus node dysfunction without a pacemaker, high-grade AV block, ventricular fibrillation, known hypersensitivity to digoxin, and uncontrolled hyperkalemia. Relative cautions apply to patients with thyroid disorders, electrolyte disturbances (especially low potassium or magnesium), and acute myocardial infarction. A comprehensive assessment-including renal function, baseline ECG, and serum electrolytes-is essential before initiating therapy. --- ## 7. Buying Digoxin from [our online pharmacy](https://liabilis.com/order-digoxin-online-en.html) ### Why Choose Our Service? Accessing digoxin can be challenging when local pharmacies experience stock shortages or when insurance coverage limits out-of-pocket costs. Our platform offers a reliable avenue to obtain the generic medication at a price close to the manufacturer’s baseline, helping you avoid the financial strain of brand-only options. ### Quality & Safety Assurance We partner with licensed international pharmacies to ensure quality and authenticity. Every shipment is sourced from facilities that comply with recognized regulatory frameworks such as the FDA, EMA, or comparable national authorities. ### Pricing & Access Because digoxin is available as a generic, the cost is markedly lower than that of branded Lanoxin. Our service highlights these savings, making long-term therapy more affordable for patients managing chronic cardiac conditions. ### Discreet Delivery Orders are dispatched in neutral packaging, respecting your privacy. Express delivery typically arrives within 7 days, while standard airmail reaches most destinations in approximately 3 weeks. Tracking information is provided for each shipment, so you can monitor progress securely. --- ## 8. Use: Dosing, Missed Dose, Overdose **Standard dosing (adults):** - Initial dose: .25 mg orally once daily (adjusted for renal function, age, and body weight). - Maintenance dose: .125-.25 mg once daily, titrated to achieve a therapeutic serum concentration (.5-2. ng/mL). **Missed dose:** - If you realize the missed dose within 6 hours, take it immediately. - If more than 6 hours have passed, skip the missed tablet and resume the regular schedule. Do not double-dose. **Suspected overdose:** - Symptoms may include nausea, vomiting, visual disturbances (yellow-green halos), confusion, and cardiac arrhythmias. - Seek emergency medical care promptly; treatment may involve activated charcoal, electrolyte correction, and digoxin-specific antibody fragments (Digibind) under hospital supervision. **Practical precautions:** - Take digoxin with or without food, but be consistent each day. - Avoid large amounts of caffeine or alcohol, which can exacerbate arrhythmias. - Do not operate heavy machinery if you feel dizzy or experience visual changes. --- ## 9. Safety Information ### ⚠️ Who Should Not Take Digoxin - Patients with **uncontrolled ventricular fibrillation** or ventricular tachycardia. - Individuals with **high-grade AV block** (second-degree type II or third-degree) unless a permanent pacemaker is installed. - Those with **known hypersensitivity** to digoxin or any excipients in the tablet. - **Severe hyperkalemia** (serum potassium > 5.5 mmol/L) due to heightened risk of toxicity. ### Common Side Effects - **Gastrointestinal:** nausea, vomiting, loss of appetite. - **Neurologic:** fatigue, headache, visual disturbances (blurred vision, halos). - **Cardiac:** mild bradycardia, premature ventricular contractions. These effects are usually mild and often diminish with dose adjustment. ### Serious Side Effects (Seek Immediate Medical Help) - **Life-threatening arrhythmias:** ventricular tachycardia, ventricular fibrillation, high-grade AV block. - **Severe hyperkalemia:** muscle weakness, paralysis, metabolic acidosis. - **Acute confusional state** or hallucinations. If any of these occur, contact emergency services without delay. ### Drug & Food Interactions - **Electrolyte-altering diuretics** (e.g., furosemide) → increase toxicity risk; monitor potassium and magnesium. - **Beta-blockers** (e.g., metoprolol) → additive bradycardia; dose may need reduction. - **Calcium channel blockers** (verapamil, diltiazem) → enhanced AV-node slowing; close ECG monitoring required. - **Amiodarone** → raises digoxin levels; consider dose reduction. - **Macrolide antibiotics** (erythromycin, clarithromycin) → inhibit hepatic metabolism, elevating serum concentrations. - **St. John’s Wort** → may reduce digoxin levels via CYP3A4 induction. - **High-potassium foods** (bananas, oranges) → generally safe, but in the setting of renal impairment careful electrolyte monitoring is essential. --- ## 10. Off-Label and Investigational Uses of Digoxin - **Paroxysmal Supraventricular Tachycardia (PSVT)** - Small case series suggest digoxin may aid in rate control when conventional agents fail, though evidence is limited. - **Dilated Cardiomyopathy** - Some clinicians use digoxin to augment contractility in advanced disease, but large trials have not demonstrated mortality benefit. - **Neuroprotective Research** - Pre-clinical studies explore digoxin’s effect on cellular ion transport in neurodegenerative models; human data remain exploratory. *Off-label use should only be considered under the direct supervision of a qualified healthcare provider.* --- ## 11. Storage & Handling - Keep tablets at **room temperature (20-25 °C)**; avoid excessive heat or freezing. - Store in a **dry place**, protected from moisture and direct sunlight. - Keep the container tightly closed and out of reach of children. - Do not use tablets past the **expiration date** printed on the package. - For safe disposal, return unused medication to a pharmacy-based take-back program or follow local hazardous-waste guidelines. --- ## 12. Frequently Asked Questions **Practical Use & Lifestyle** - **Can I travel internationally with digoxin?** Yes. Carry the medication in its original labeled container, accompanied by a copy of the prescription and a brief note from your physician stating the medical necessity. - **Does grapefruit juice affect digoxin levels?** Grapefruit has minimal impact on digoxin metabolism, but it can interfere with other cardiac drugs. Nonetheless, maintain consistent dietary habits and discuss any major changes with your pharmacist. - **Is it safe to take digoxin while exercising?** Moderate activity is generally safe, but intense exercise may precipitate arrhythmias in susceptible individuals. Monitor symptoms and discuss an appropriate activity plan with your clinician. **Product & Formulation Details** - **What does a .25 mg digoxin tablet look like?** The tablet is typically round, white to off-white, and may be marked with the imprint “.25” on one side. Appearance can vary by manufacturer; always verify the imprint before ingestion. - **Are there any inactive ingredients I should be aware of?** Common excipients include lactose, starch, and magnesium stearate. If you have known allergies to these substances, consult your pharmacist for a suitable formulation. **Regulatory & Safety Nuances** - **Will digoxin appear on a standard drug test?** Routine workplace drug screens do not test for digoxin, as it is not a substance of abuse. Specialized cardiac medication panels may detect it, but such testing is uncommon. - **Is digoxin approved for use in pregnancy?** Digoxin is classified as **Category C** (risk cannot be ruled out) in the United States. It may be prescribed during pregnancy when the potential benefit justifies the potential risk, typically under close obstetric and cardiology supervision. - **How does kidney function influence digoxin dosing?** Since digoxin is eliminated primarily by the kidneys, reduced renal clearance (eGFR < 50 mL/min) necessitates lower doses and extended dosing intervals to avoid toxicity. **Scientific & Clinical Curiosity** - **When was digoxin first introduced into clinical practice?** Digoxin’s therapeutic use dates back to the early 19th century, following isolation from foxglove plants in 1785 and subsequent formal medical adoption in the 182s. - **What were the landmark trials that defined its role in heart failure?** The DIG (Digitalis Investigation Group) trial, published in 1997, demonstrated modest reductions in hospitalization for heart failure but no significant mortality benefit, shaping current guideline recommendations. --- ## 13. Glossary **Therapeutic Window** : The concentration range of a drug in the bloodstream where it is effective without producing unacceptable toxicity. **Negative Chronotropy** : A property of a medication that slows the heart rate by reducing the speed of electrical conduction, particularly through the AV node. **Bio-equivalence** : Demonstration that a generic drug delivers the same amount of active ingredient into a patient’s bloodstream as the branded reference product, under similar conditions. --- ## 14. Disclaimer The information provided about **Digoxin** is for general knowledge only. It does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. [our online pharmacy](https://liabilis.com/order-digoxin-online-en.html) offers access to **Digoxin** for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.