--- title: Buy Capecitabine 500mg Cancer Treatment Pills description: Capecitabine chemotherapy treats breast, colon, and gastric cancers. Order verified cancer medication with care. type: product language: en url: https://liabilis.com/order-capecitabine-online-en.html availability: in_stock shipping: - type: Standard Airmail price: 10.00 currency: USD area: Worldwide time: 14-21 days - type: Tracked Express price: 30.00 currency: USD area: Worldwide tracking: true time: 5-9 days price_min: 365.74 price_max: 1049.99 currency: USD offers: - name: 500mg x 100 pills price: 365.74 - name: 500mg x 200 pills price: 702.99 - name: 500mg x 300 pills price: 1049.99 --- # Buy Capecitabine 500mg Cancer Treatment Pills Capecitabine is an oral chemotherapy medication that converts to 5-fluorouracil in the body to attack cancer cells. Originally developed by Roche, it is used to treat breast cancer, colorectal cancer, and gastric cancer. This treatment is designed for adults undergoing cancer therapy under medical supervision. Our pharmacy provides Capecitabine in precise 500mg tablet form for accurate dosing in cancer treatment regimens. ## Pricing and Options | Dosage | Pack Size | Price (USD) | Price Per Pill | Status | | :--- | :--- | :--- | :--- | :--- | | **500mg** | 100 pills | **$365.74** | $3.66 | In Stock | | **500mg** | 200 pills | **$702.99** | $3.52 | In Stock | | **500mg** | 300 pills | **$1049.99** | $3.50 | In Stock | [Buy Now](https://liabilis.com/order-capecitabine-online-en.html) ## Introduction Capecitabine is an oral chemotherapy agent used to treat several solid tumors. The active ingredient is capecitabine, supplied as a 500 mg pill. It belongs to the antimetabolite class of drugs and acts as a pro-drug of 5-fluorouracil (5-FU). Capecitabine is indicated for metastatic colorectal cancer, adjuvant colon cancer, metastatic breast cancer, and certain gastric cancers. The medication is administered in cycles, typically two weeks of dosing followed by a one-week rest period. ## Quick Reference Facts **Active Ingredient** : capecitabine **Form** : pill 500 mg **Primary Uses** : metastatic colorectal cancer, adjuvant colon cancer, metastatic breast cancer, gastric cancer ## What is Capecitabine? Capecitabine is a chemically synthesized, oral pro-drug that is converted in the body to 5-fluorouracil, a pyrimidine analog that interferes with DNA synthesis. It is classified as a fluoropyrimidine antimetabolite. The drug was first approved in the United States in 1998 and is marketed worldwide under various brand names, most notably Xeloda. As a generic medication, capecitabine provides the same therapeutic effect as brand-named products while offering a lower cost alternative. It is manufactured by multiple licensed pharmaceutical companies that meet international quality standards. ## How Capecitabine Works After ingestion, capecitabine is absorbed through the gastrointestinal tract and undergoes a three-step enzymatic conversion. First, hepatic carboxylesterase converts it to 5′-deoxy-5-fluorocytidine (5′-DFCR). Second, cytidine deaminase in the liver and tumor tissue transforms 5′-DFCR to 5′-deoxy-5-fluorouridine (5′-DFUR). Finally, thymidine phosphorylase-an enzyme that is found higher levels in many cancer cells-converts 5′-DFUR to the active metabolite 5-fluorouracil (5-). 5-FU incorporates into RNA and inhibits thymidylate synthase, disrupting DNA synthesis and triggering apoptosis preferentially in rapidly dividing tumor cells. Because the last conversion step occurs largely within the tumor microenvironment, capecitabine achieves higher intratumoral concentrations of 5-FU while limiting systemic exposure, which helps reduce certain toxicities compared with intravenous 5-FU. ## Conditions Treated with Capecitabine - **Metastatic colorectal cancer** - Capecitabine is used alone or in combination with other agents such as oxaliplatin or irinotecan. It extends progression-free survival by targeting proliferating colorectal tumor cells. - **Adjuvant colon cancer** - Following surgical resection, capecitabine is given to eradicate microscopic disease and lower the risk of recurrence. - **Metastatic breast cancer** - When combined with taxanes or as monotherapy, capecitabine provides an oral option for patients whose disease has progressed after anthracycline and taxane therapy. - **Advanced gastric cancer** - In patients with unresectable or metastatic gastric adenocarcinoma, capecitabine is part of combination regimens (e.g., with cisplatin) that improve overall survival. - **Pancreatic cancer (select indications)** - Capecitabine may be added to gemcitabine-based protocols in certain jurisdictions to enhance antitumor activity. ## Is Capecitabine the Right Medication for You? Capecitabine is appropriate for adult patients with the above-listed cancers who have adequate organ function (renal clearance ≥50 mL/min, hepatic bilirubin ≤1.5 × ULN) and can swallow oral tablets. It is especially useful for patients who prefer an oral regimen over continuous intravenous infusion, allowing treatment at home. Contraindications include known hypersensitivity to capecitabine or other fluoropyrimidines, severe renal impairment (creatinine clearance <30 mL/min), severe hepatic dysfunction, and pregnancy or lactation. Patients with dihydropyrimidine dehydrogenase (DPD) deficiency are at high risk for severe toxicity and should avoid the drug. Clinicians typically select capecitabine when the tumor expresses thymidine phosphorylase, when a patient’s performance status permits oral therapy, and when the treatment goal is either curative (adjuvant setting) or disease control in metastatic disease. ## Buying Capecitabine from [our online pharmacy](https://liabilis.com/order-capecitabine-online-en.html) ### Why Choose Our Service? [our online pharmacy](https://liabilis.com/order-capecitabine-online-en.html) streamlines access to essential oncology medicines, helping patients overcome cost barriers and geographic shortages. By sourcing capecitabine through verified international partners, we provide a reliable route to obtain the medication when local pharmacies cannot supply it promptly. ### Quality & Safety Assurance We partner with licensed international pharmacies to ensure quality and authenticity. All capecitabine tablets are manufactured in GMP-certified facilities and undergo independent verification before shipment. ### Pricing & Access Because capecitabine is available as a generic, the price is significantly lower than brand-name equivalents such as Xeloda. Our pricing reflects near-manufacturer cost, offering an affordable option for patients managing long-term therapy. ### Discreet Delivery Orders are packed in unmarked, secure containers and dispatched via express courier, typically arriving within 7 days. Standard airmail delivery takes roughly three weeks. Both options prioritize privacy and timely receipt of your medication. ## Use: Dosing, Missed Dose, Overdose - **Standard dosing** - The most common regimen is 125 mg/m² per day, divided into two doses taken 12 hours apart, for 14 consecutive days followed by a 7-day rest period. Tablets are 500 mg; the exact number of tablets per dose depends on the patient’s calculated body surface area. - **Missed dose** - If a dose is forgotten and the scheduled time is less than 12 hours away, take it as soon as remembered. If more than 12 hours have passed, skip the missed dose and resume the regular schedule. Do not double-dose. - **Overdose** - Suspected overdose may present with severe nausea, vomiting, diarrhea, or confusion. Seek emergency medical care immediately. Supportive measures (hydration, anti-emetics, and monitoring of blood counts) are the mainstays of treatment. - **Administration tips** - Take capecitabine within 30 minutes after a meal or a light snack; food improves absorption. Avoid alcohol, as it can increase the risk of severe stomach upset. Do not operate heavy machinery if you experience significant fatigue or neuropathy. ## Safety Information ### ⚠️ Who Should Not Take Capecitabine - Patients with documented hypersensitivity to capecitabine, fluoropyrimidines, or any tablet excipients. - Individuals with severe renal dysfunction (creatinine clearance <30 mL/min) or significant hepatic impairment (bilirubin >1.5 × ULN). - Pregnant or breastfeeding women; the drug is teratogenic and can be excreted in breast milk. - Patients with known DPD enzyme deficiency, as they are at high risk for life-threatening toxicity. ### Common Side Effects - **Gastrointestinal:** Nausea, vomiting, diarrhea, and abdominal cramping (often mild to moderate). - **Dermatologic:** Hand-foot syndrome (palmar-plantar erythrodysesthesia), characterized by redness, swelling, or tenderness of the palms and soles. - **Hematologic:** Mild to moderate neutropenia, anemia, or thrombocytopenia; routine blood count monitoring is advised. - **General:** Fatigue, loss of appetite, and mild alopecia. Most of these effects are manageable with dose adjustments, supportive care, or temporary treatment interruption. ### Serious Side Effects (Seek Immediate Medical Help) - **Severe neutropenia** (absolute neutrophil count <500 cells/µL) with fever or infection. - **Profuse diarrhea** or watery stools lasting more than 48 hours, which may lead to dehydration. - **Persistent vomiting** preventing oral intake. - **Severe hand-foot syndrome** causing blistering or ulceration. - **Signs of allergic reaction:** Rash, itching, swelling of face or throat, difficulty breathing. If any of these occur, discontinue capecitabine and contact a healthcare professional promptly. ### Drug & Food Interactions - **Anticoagulants (e.g., warfarin):** Capecitabine may enhance anticoagulant effects; monitor INR closely. - **Other cytotoxic agents:** Combined use can increase myelosuppression; dose adjustments may be necessary. - **Corticosteroids:** May increase risk of hand-foot syndrome; monitor skin regularly. - **Alcohol:** Excessive intake can worsen gastrointestinal toxicity. - **Folate supplementation:** High-dose folinic acid can reduce capecitabine-related toxicity, but must be prescribed by a clinician. Patients should disclose all concurrent medications, including over-the-counter products and herbal supplements, to their prescribing physician. ## Off-Label and Investigational Uses of Capecitabine Capecitabine has been explored in several off-label settings: - **Head and neck squamous cell carcinoma:** Small phase II trials reported disease control when combined with radiotherapy. - **Cholangiocarcinoma:** Some centers use capecitabine as part of a gemcitabine-based regimen, with modest response rates. - **Lower-dose maintenance therapy:** Investigations into continuous low-dose capecitabine for prolonged disease stabilization have shown tolerable safety profiles. These applications are not approved by major regulatory agencies and should only be undertaken under direct supervision of a qualified oncology specialist. ## Storage & Handling - Store capecitabine tablets at room temperature (15-30 °C) in a dry place, protected from light and moisture. - Keep the container tightly closed and out of reach of children. - Do not use tablets past the expiration date printed on the packaging. - Dispose of unused medication according to local regulations or return to a pharmacy for safe disposal. ## Frequently Asked Questions **Practical Use & Lifestyle** - **Can I travel internationally with capecitabine?** Yes. Carry the medication in its original container, include a copy of your prescription, and declare it at customs if required. Keep the tablets sealed from heat and humidity. - **Should I take capecitabine with meals or on an empty stomach?** Take each dose within 30 minutes after a meal or light snack. Food improves absorption and reduces stomach irritation. - **Is it safe to consume caffeine while on capecitabine?** Moderate caffeine intake is generally permissible, but excessive amounts may worsen anxiety or insomnia, which can already be side effects of chemotherapy. - **Can I exercise while receiving capecitabine?** Light to moderate activity is encouraged, but avoid high-impact workouts if you develop hand-foot syndrome or severe fatigue. **Product & Formulation Details** - **What do capecitabine tablets look like?** The 500 mg tablets are round, white to off-white, and may be film-coated. Imprints vary by manufacturer; verify the imprint against the packaging label. - **Are there any inactive ingredients I should be aware of?** Common excipients include lactose, magnesium stearate, and microcrystalline cellulose. Patients with severe lactose intolerance should discuss alternatives with their pharmacist. - **Can the tablets be split or crushed?** Capecitabine tablets are not scored and should be swallowed whole. Splitting or crushing may affect drug release and increase toxicity risk. **Regulatory & Safety Nuances** - **Will capecitabine appear on a standard drug test?** Routine occupational drug screens do not detect chemotherapy agents. However, specialized testing could identify fluoropyrimidines if specifically requested. - **Is capecitabine approved for use in the United Kingdom?** Yes. The Medicines and Healthcare products Regulatory Agency (MHRA) has approved capecitabine for the indications listed above. - **Is capecitabine considered safe for elderly patients?** Age alone is not a contraindication, but older adults often have reduced renal function, necessitating dose adjustments and closer monitoring. **Scientific & Clinical Curiosity** - **What landmark trial established capecitabine’s efficacy in colorectal cancer?** The MOSAIC trial demonstrated that capecitabine, combined with oxaliplatin (the XELOX regimen), improved disease-free survival compared with 5-FU alone. **How does capecitabine differ from intravenous 5-FU?** Capecitabine provides oral administration with tumor-selective activation, resulting in higher intratumoral 5-FU concentrations and a more convenient dosing schedule than continuous IV infusion. ## Glossary **Pro-drug** : An inactive compound that is metabolized in the body to produce an active therapeutic agent. **Hand-foot syndrome** : A dermatologic toxicity causing redness, swelling, and pain on the palms and soles, commonly associated with fluoropyrimidines. **Thymidine phosphorylase** : An enzyme that converts capecitabine’s intermediate metabolite to 5-fluorouracil, largely expressed in tumor tissue. **BSA (Body Surface Area)** : A calculation based on height and weight used to determine individualized chemotherapy dosing. **DPD deficiency** : A genetic lack of dihydropyrimidine dehydrogenase, the enzyme responsible for breaking down fluoropyrimidines, leading to severe toxicity. ## Disclaimer The information provided about **Capecitabine** is for general knowledge only. It does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. [our online pharmacy](https://liabilis.com/order-capecitabine-online-en.html) offers access to **Capecitabine** for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.